Stimuli‐Responsive Silica Silanol Conjugates: Strategic Nanoarchitectonics in Targeted Drug Delivery

S Mohanan, X Guan, M Liang, A Karakoti, A Vinu - Small, 2024 - Wiley Online Library
The design of novel drug delivery systems is exceptionally critical in disease treatments.
Among the existing drug delivery systems, mesoporous silica nanoparticles (MSNs) have …

Mesoporous silica nanotechnology: promising advances in augmenting cancer theranostics

Y Dutta Gupta, Y Mackeyev, S Krishnan… - Cancer …, 2024 - Springer
Owing to unique facets, such as large surface area, tunable synthesis parameters, and ease
of functionalization, mesoporous silica nanoparticles (MSNs) have transpired as a …

Design and synthesis of cabazitaxel loaded core‐shell mesoporous silica nanoparticles with different morphologies for prostate cancer therapy

S Mohanan, CI Sathish, K Ramadass, M Liang, A Vinu - Small, 2024 - Wiley Online Library
In this work, the synthesis of core‐shell ordered mesoporous silica nanoparticles (CSMS)
with tunable particle size and shape through a dual surfactant‐assisted approach is …

Microfluidic‐assisted production of gastro‐resistant active‐targeted diatomite nanoparticles for the local release of galunisertib in metastatic colorectal cancer cells

C Tramontano, JP Martins, L De Stefano… - Advanced …, 2023 - Wiley Online Library
The oral route is highly desirable for colorectal cancer (CRC) treatment because it allows
concentrating the drug in the colon and achieving a localized effect. However, orally …

A dual protective drug delivery system based on lipid coated core-shell mesoporous silica for efficient delivery of cabazitaxel to prostate cancer cells

S Mohanan, CI Sathish, TJ Adams, S Kan… - Bulletin of the …, 2023 - academic.oup.com
Many advancements are happening in drug delivery to develop an excellent nanocarrier to
deliver drugs to target sites bypassing clinical barriers, thereby improving cellular uptake …

Development and DoE-ANN based optimization of novel swellable matrix-diffusible doxorubicin loaded zinc oxide nanoflowers using sonochemical-precipitation …

S Ijaz, M Sultana, R Shamim, NI Bukhari - International Journal of …, 2023 - Elsevier
This research aimed to acquire doxorubicin loaded zinc oxide nanoflowers (DOX-ZnO-NFs)
for intracellular drug cargo possessing a synergistic in-vitro anticancer activity with minimal …

[HTML][HTML] Silica nanoparticles in medicine: overcoming pathologies through advanced drug delivery, diagnostics, and therapeutic strategies

CL Nicolae, DC Pîrvulescu, AM Antohi… - … of Morphology and …, 2024 - pmc.ncbi.nlm.nih.gov
Over the last decades, silica nanoparticles (SiNPs) have been studied for their applications
in biomedicine as an alternative used for conventional diagnostics and treatments. Since …

Combinatorial treatment using bevacizumab/pemetrexed loaded core-shell silica nanoparticles for non-small cell lung cancer

D Radhakrishnan, V Patel, S Mohanan… - … and Technology of …, 2023 - Taylor & Francis
Non-small cell lung cancer (NSCLC) is a life-threatening cancer associated with a higher
mortality rate. Despite promising results shown by combination therapies, there remains a …

[HTML][HTML] Nanotechnology and nucleic acid nanoparticles for treatment of metabolic disorders

DT Chu, HV Thi, TT Nguyen, TD Vu, YVN Thi, I Mani… - OpenNano, 2023 - Elsevier
Metabolic disorders result from inborn and acquired dysfunction of organs and tissues that
are responsible for producing energy in the body. These diseases are now among the most …

Emerging multifunctional carbon‐nanomaterial‐based biosensors for cancer diagnosis

JSJ Britto, X Guan, TKA Tran, Z Lei, R Bahadur… - Small …, 2024 - Wiley Online Library
Despite significant advancements in medical technology, cancer remains the world's second‐
leading cause of death, largely attributed to late‐stage diagnoses. While traditional cancer …