Peptide-based vaccines for tuberculosis
W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …
Interaction of SARS-CoV-2 with host cells and antibodies: experiment and simulation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …
Immunogenomics guided design of immunomodulatory multi-epitope subunit vaccine against the SARS-CoV-2 new variants, and its validation through in silico …
Reports of the novel and more contagious strains of SARS-CoV-2 originating in different
countries have further aggravated the pandemic situation. The recent substitutions in spike …
countries have further aggravated the pandemic situation. The recent substitutions in spike …
COVID-19 pandemic: the delta variant, T-cell responses, and the efficacy of developing vaccines
Background The mayhem COVID-19 that was ushered by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV2) was declared pandemic by the World Health …
syndrome coronavirus 2 (SARS-CoV2) was declared pandemic by the World Health …
Reverse vaccinology assisted design of a novel multi-epitope vaccine to target Wuchereria bancrofti cystatin: An immunoinformatics approach
Proteases are the critical mediators of immunomodulation exerted by the filarial parasites to
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …
A novel vaccine based on SARS-CoV-2 CD4+ and CD8+ T cell conserved epitopes from variants Alpha to Omicron
I Palatnik-de-Sousa, ZS Wallace, SC Cavalcante… - Scientific reports, 2022 - nature.com
COVID-19 caused, as of September, 1rst, 2022, 599,825,400 confirmed cases, including
6,469,458 deaths. Currently used vaccines reduced severity and mortality but not virus …
6,469,458 deaths. Currently used vaccines reduced severity and mortality but not virus …
Bioengineering of novel non-replicating mRNA (NRM) and self-amplifying mRNA (SAM) vaccine candidates against SARS-CoV-2 using immunoinformatics approach
Presently, the world needs safe and effective vaccines to overcome the COVID-19
pandemic. Our work has focused on formulating two types of mRNA vaccines that differ in …
pandemic. Our work has focused on formulating two types of mRNA vaccines that differ in …
[HTML][HTML] A next-generation vaccine candidate using alternative epitopes to protect against Wuhan and all significant mutant variants of SARS-CoV-2: an …
Newly emerging significant SARS-CoV-2 variants such as B. 1.1. 7, B. 1.351, and B. 1.1. 28
are the variant of concern (VOC) for the human race. These variants are getting challenging …
are the variant of concern (VOC) for the human race. These variants are getting challenging …
Computational design of a multi-epitope vaccine candidate against Langya henipavirus using surface proteins
Abstract In July 2022, Langya henipavirus (LayV) was identified in febrile patients in China.
There is currently no approved vaccine against this virus. Therefore, this research aimed to …
There is currently no approved vaccine against this virus. Therefore, this research aimed to …
In silico and in vivo evaluation of SARS-CoV-2 predicted epitopes-based candidate vaccine
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, the causative agent of
coronavirus disease (COVID-19)) has caused relatively high mortality rates in humans …
coronavirus disease (COVID-19)) has caused relatively high mortality rates in humans …