Current trends of essential trace elements in patients with chronic liver diseases

T Himoto, T Masaki - Nutrients, 2020 - mdpi.com
Essential trace elements play crucial roles in the maintenance of health, since they are
involved in many metabolic pathways. A deficiency or an excess of some trace elements …

Low hepcidin in liver fibrosis and cirrhosis; a tale of progressive disorder and a case for a new biochemical marker

D Vela - Molecular Medicine, 2018 - Springer
Liver fibrosis is a precursor of liver cirrhosis, which is associated with increased mortality.
Though liver biopsy remains the gold standard for the diagnosis of fibrosis, noninvasive …

Relationship between hepatitis C virus infection and iron overload

DM Zou, WL Sun - Chinese Medical Journal, 2017 - journals.lww.com
Objective: The aim of this study was to summarize the interactions between hepatitis C virus
(HCV) infection and iron overload, and to understand the mechanisms of iron overload in …

Salmonella effector SpvB aggravates dysregulation of systemic iron metabolism via modulating the hepcidin−ferroportin axis

Q Deng, S Yang, L Sun, K Dong, Y Li, S Wu… - Gut Microbes, 2021 - Taylor & Francis
Iron withholding, an essential component of nutritional immunity, plays a fundamental role in
host resistance to Salmonella infection. Our previous study showed that SpvB, an important …

Evolution of ferritin levels in hepatitis C patients treated with antivirals

ML Chang, JH Hu, CH Yen, KH Chen, CJ Kuo… - Scientific reports, 2020 - nature.com
The evolution of ferritin levels in hepatitis C virus (HCV)-infected patients with sustained
virological responses (SVRs) following various therapy regimens remains elusive. An 8-year …

[HTML][HTML] Iron as a therapeutic target in chronic liver disease

E Kouroumalis, I Tsomidis… - World Journal of …, 2023 - ncbi.nlm.nih.gov
It was clearly realized more than 50 years ago that iron deposition in the liver may be a
critical factor in the development and progression of liver disease. The recent clarification of …

Metabolic reprogramming and immune regulation in viral diseases

GV Ganesh, RK Mohanram - Reviews in medical virology, 2022 - Wiley Online Library
The recent outbreak and transmission of the severe acute respiratory syndrome coronavirus
2 (SARS‐CoV‐2) worldwide and the ensuing coronavirus disease 2019 (COVID‐19) …

Iron deficiency, anemia, and the immune system

AM Mitterstiller, L von Raffay, M Nairz - Nutritional Anemia, 2022 - Springer
Iron homeostasis is critical for human health, because both too little and too much iron may
have severe clinical consequences. No other element can replace iron as component of …

Iron redox pathway revealed in ferritin via electron transfer analysis

P Chen, E De Meulenaere, DD Deheyn, PR Bandaru - Scientific reports, 2020 - nature.com
Ferritin protein is involved in biological tissues in the storage and management of iron-an
essential micro-nutrient in the majority of living systems. While there are extensive studies …

Infection-iron interaction during COVID-19 pandemic: Time to re-design iron supplementation programs

LF Augustine, V Mullapudi, S Subramanian… - Medical …, 2020 - ncbi.nlm.nih.gov
Several countries with high prevalence of nutritional anaemia implement population based
iron supplementation programs for anaemia reduction. With large population sections in …