This article summarizes a variety of physical mechanisms proposed in the literature, which
can generate micro-and nanodomains in multicomponent lipid bilayers and biomembranes …

Ever since the raft model for biomembranes has been proposed, the traditional view of
biomembranes based on the fluid-mosaic model has been altered. In the raft model …

The lipid raft hypothesis presents insights into how the cell membrane organizes proteins
and lipids to accomplish its many vital functions. Yet basic questions remain about the …

According to the lipid raft hypothesis, biological lipid membranes are laterally
heterogeneous and filled with nanoscale ordered “raft” domains, which are believed to play …

To explain the appearance of heterogeneities in the plasma membrane, I propose a
hypothesis which begins with the observation that fluctuations in the membrane curvature …

Nanometer-scale domains in cholesterol-rich model membranes emulate lipid rafts in cell
plasma membranes (PMs). The physicochemical mechanisms that maintain a finite, small …

We present a theory of inhomogeneities in the plasma membrane, or rafts, that can exist in
both leaves of the plasma membrane. We note that although neither of the major …

The cellular membranes are composed of hundreds of components such as lipids, proteins,
and sterols that are chemically and physically distinct from each other. The lipid–lipid and …

Experiments have shown that homologous Ras proteins containing different lipid
modification, which is required for membrane binding, form nonoverlapping nanoclusters on …

A ternary mixture model is proposed to describe composition fluctuations in mixed
membranes composed of saturated, unsaturated, and hybrid lipids (with one saturated and …