Infertility affects a significant number of couples worldwide and its incidence is increasing.
While assisted reproductive technologies (ART) have revolutionized the treatment …

Primary ovarian insufficiency (POI) is a heterogeneous disease resulting from non-functional
ovaries in women before the age of 40. It is characterized by primary amenorrhea or …

Delaying childbearing age has become a trend in modern times, but it has also led to a
common challenge in clinical reproductive medicine—diminished ovarian reserve (DOR) …

Abstract Bone morphogenetic protein 15 (BMP15) is specifically expressed in oocytes in
pigs at all stages from early stages to ovulation and has an important role in oocyte …

骨形态发生蛋白15 (bone morphogenetic protein 15, BMP15) 作为卵母细胞分泌因子,
在调控卵泡发育过程中起着重要的作用. BMP15 通过协同双调蛋白, 上调卵丘扩张基因的表达 …

Premature ovarian failure (POF) is an insidious cause of female infertility and a devastating
condition for women. POF also has a strong familial and heterogeneous genetic …

Introduction Premature ovarian insufficiency (POI) is a primary cause of infertility with
variable clinical manifestations. POI is a multifactorial disease with both environmental and …

Abstract Bone morphogenetic protein 15 (BMP15) is an oocyte‐specific growth factor
important for successful female reproduction in mammals. While mutations in BMP15/Bmp15 …

Premature Ovarian Insufficiency (POI) is a highly heterogeneous condition characterized by
ovarian dysfunction in women occurring before the age of 40, representing a significant …

生长分化因子-9 (growth differentiation factor-9, GDF-9) 和骨形态生成蛋白-15 (bone
morphogenetic protein-15, BMP-15) 是转化生长因子-3 (transforming growth factor-3, TGF-3) …