Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …

The emerging interest in brain fluid transport has prompted a need for techniques that
provide an understanding of what factors regulate cerebrospinal fluid (CSF) production …

Abstract Over the past 10-20 years, neuroscience witnessed an explosion in the use of non-
invasive imaging methods, particularly magnetic resonance imaging (MRI), to study brain …

Over the past fifteen years, focused ultrasound coupled with intravenously administered
microbubbles (FUS) has been proven an effective, non-invasive technique to open the blood …

Background Anesthetized animal models are used extensively during neurophysiological
and behavioral studies despite systemic effects from anesthesia that undermine both …

Isoflurane is a commonly used inhalational anesthetic, clinically and in animal experimental
studies. Although it has been reported as safe, recent findings suggest that despite …

Traumatic brain injury (TBI) is often accompanied by hemorrhage, and treatment of
hemorrhagic shock (HS) after TBI is particularly challenging because the two therapeutic …

Background Marmosets are a powerful, emerging model for human behavior and
neurological disorders. However, longitudinal imaging modalities that visualize both cellular …

Background Cerebral blood flow (CBF) plays an important role in neurological recovery after
cardiac arrest (CA) resuscitation. However, the variations of CBF recovery in distinct brain …

Nitric oxide (NO) produced by endothelial NO synthase (eNOS) is a key regulator of cerebral
blood flow (CBF) dynamics. Mice with eNOS deficiency (eNOS−/-) display age-related …