Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary
kidney disease and one of the most common causes of end-stage kidney disease. Multiple …

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

Mitochondria are energy-producing organelles that not only satisfy the high metabolic
demands of the kidney but sense and respond to kidney injury-induced oxidative stress and …

Ischemia/reperfusion injury (IRI) is prone to occur after kidney transplantation, leading to
delayed graft function (DGF). MicroRNAs play a crucial role in the pathogenesis of …

The kidney is a highly metabolic organ and uses high levels of ATP to maintain electrolyte
and acid-base homeostasis and reabsorb nutrients. Energy depletion is a critical factor in …

Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common,
potentially lethal, monogenic diseases and is caused predominantly by mutations in …

Autosomal dominant polycystic kidney disease (ADPKD), caused by mutations in either
PKD1 or PKD2 genes, is one of the most common human monogenetic disorders and the …

Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disorder
marked by numerous progressively enlarging kidney cysts. Mettl3, a methyltransferase that …

During the last decades, basic and translational research has enabled great improvements
in the clinical management of cancer. However, scarcity of complete remission and many …