Dietary nitrate and nitric oxide metabolism mouth, circulation, skeletal muscle, and exercise performance

AM Jones, A Vanhatalo, DR Seals, MJ Rossman… - 2020 - nih.brage.unit.no
Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in myriad
physiological processes including the regulation of vascular tone, neurotransmission …

Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency

A Lichota, L Gwozdzinski, K Gwozdzinski - European Journal of Medicinal …, 2019 - Elsevier
The term varicose vein refers to the twisted and swollen vein visible under the skin surface
which occurs most commonly in the leg. Epidemiological studies report a varying …

15N‐labeled dietary nitrate supplementation increases human skeletal muscle nitrate concentration and improves muscle torque production

S Kadach, JW Park, Z Stoyanov, MI Black… - Acta …, 2023 - Wiley Online Library
Abstract Aim Dietary nitrate (NO3−) supplementation increases nitric oxide bioavailability
and can enhance exercise performance. We investigated the distribution and metabolic fate …

The role of oxidative stress, adhesion molecules and antioxidants in preeclampsia

K Haram, JH Mortensen, O Myking… - Current …, 2019 - ingentaconnect.com
Oxidative stress is a consequence of reduction in the antioxidant capacity and excessive
production of reactive oxygen and nitrogen species (ROS). Oxidative agents, which are …

Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions

SP Rendić, RD Crouch, FP Guengerich - Archives of Toxicology, 2022 - Springer
This is an overview of the metabolic reactions of drugs, natural products, physiological
compounds, and other (general) chemicals catalyzed by flavin monooxygenase (FMO) …

Aldehyde oxidase and its role as a drug metabolizing enzyme

D Dalvie, L Di - Pharmacology & therapeutics, 2019 - Elsevier
Aldehyde oxidase (AO) is a cytosolic enzyme that belongs to the family of structurally related
molybdoflavoproteins like xanthine oxidase (XO). The enzyme is characterized by broad …

Hyperuricemia: a key contributor to endothelial dysfunction in cardiovascular diseases

X Wei, M Zhang, S Huang, X Lan, J Zheng… - The FASEB …, 2023 - Wiley Online Library
As an end product of purine metabolism, uric acid (UA) is a major endogenous antioxidant in
humans. However, impaired UA synthesis and excretion can lead to hyperuricemia (HUA) …

Role of nitrate reductase in NO production in photosynthetic eukaryotes

M Tejada-Jimenez, A Llamas, A Galván, E Fernández - Plants, 2019 - mdpi.com
Nitric oxide is a gaseous secondary messenger that is critical for proper cell signaling and
plant survival when exposed to stress. Nitric oxide (NO) synthesis in plants, under standard …

Does the micronutrient molybdenum have a role in gestational complications and placental health?

V Foteva, JJ Fisher, Y Qiao, R Smith - Nutrients, 2023 - mdpi.com
Molybdenum is an essential trace element for human health and survival, with molybdenum-
containing enzymes catalysing multiple reactions in the metabolism of purines, aldehydes …

Pseudomonas aeruginosa initiates a rapid and specific transcriptional response during surface attachment

CJ Jones, N Grotewold, DJ Wozniak… - Journal of …, 2022 - Am Soc Microbiol
Chronic biofilm infections by Pseudomonas aeruginosa are a major contributor to the
morbidity and mortality of patients. The formation of multicellular bacterial aggregates, called …