Regioselectivity in the ring opening of non-activated aziridines
In this critical review, the ring opening of non-activated 2-substituted aziridinesvia
intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship …
intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship …
An Advance on Exploring N-tert-Butanesulfinyl Imines in Asymmetric Synthesis of Chiral Amines
GQ Lin, MH Xu, YW Zhong, XW Sun - Accounts of chemical …, 2008 - ACS Publications
Although catalytic asymmetric synthesis has undergone tremendous growth in the last 30
years, chiral auxiliary-aided asymmetric synthesis continues to attract considerable …
years, chiral auxiliary-aided asymmetric synthesis continues to attract considerable …
CuH-catalyzed regioselective intramolecular hydroamination for the synthesis of alkyl-substituted chiral aziridines
This report details a general and enantioselective means for the synthesis of alkyl-
substituted aziridines. This protocol offers a direct route for the synthesis of alkyl-substituted …
substituted aziridines. This protocol offers a direct route for the synthesis of alkyl-substituted …
A Highly Efficient and Direct Approach for Synthesis of Enantiopure β-Amino Alcohols by Reductive Cross-Coupling of Chiral N-tert-Butanesulfinyl Imines with …
YW Zhong, YZ Dong, K Fang, K Izumi… - Journal of the …, 2005 - ACS Publications
A highly efficient and practical approach for the synthesis of optically pure β-amino alcohols
by the SmI2-induced reductive cross-coupling of chiral N-tert-butanesulfinyl imines with …
by the SmI2-induced reductive cross-coupling of chiral N-tert-butanesulfinyl imines with …
Scale and sustainability of marine bioprospecting for pharmaceuticals
B Hunt, ACJ Vincent - AMBIO: A Journal of the Human Environment, 2006 - BioOne
Collecting marine organisms for the discovery and development of pharmaceuticals has
been perceived variously as sustaining and threatening conservation. Our initial …
been perceived variously as sustaining and threatening conservation. Our initial …
New zinc (II)-based catalyst for asymmetric azomethine ylide cycloaddition reactions
A new chiral aziridino alcohol ligand for zinc (II)-catalyzed azomethine ylide cycloadditions
is described. In the presence of this catalyst, N-arylidene glycine methyl esters react with a …
is described. In the presence of this catalyst, N-arylidene glycine methyl esters react with a …
Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans
Sphingolipids are bio-active metabolites that show structural diversity among eukaryotes.
They are essential for growth of all eukaryotic cells but when produced in an uncontrolled …
They are essential for growth of all eukaryotic cells but when produced in an uncontrolled …
Resolution of racemic 2-aminocyclohexanol derivatives and their application as ligands in asymmetric catalysis
I Schiffers, T Rantanen, F Schmidt… - The Journal of …, 2006 - ACS Publications
A preparatively easy and efficient protocol for the resolution of racemic 2-aminocyclohexanol
derivatives is described, delivering both enantiomers with> 99% enantiomeric excess (ee) …
derivatives is described, delivering both enantiomers with> 99% enantiomeric excess (ee) …
Preparation of anti-Vicinal Amino Alcohols: Asymmetric Synthesis of d-erythro-Sphinganine, (+)-Spisulosine, and d-ribo-Phytosphingosine
EDD Calder, AM Zaed… - The Journal of Organic …, 2013 - ACS Publications
Two variations of the Overman rearrangement have been developed for the highly selective
synthesis of anti-vicinal amino alcohol natural products. A MOM ether-directed palladium (II) …
synthesis of anti-vicinal amino alcohol natural products. A MOM ether-directed palladium (II) …
Straightforward access to spisulosine and 4, 5-dehydrospisulosine stereoisomers: probes for profiling ceramide synthase activities in intact cells
JL Abad, I Nieves, P Rayo, J Casas… - The Journal of …, 2013 - ACS Publications
A stereoselective synthesis of spisulosine (ES285) and 4, 5-dehydrospisulosine
stereoisomers is described. Hydrozirconation of 1-pentadecyne with Schwartz reagent …
stereoisomers is described. Hydrozirconation of 1-pentadecyne with Schwartz reagent …