The prevalence and incidence of type 2 diabetes (T2D) among the Hispanic population in
the United States are higher than the national average. This is partly due to sociocultural …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Central (visceral) obesity is more closely associated with insulin resistance, type 2 diabetes,
and cardiovascular disease than is peripheral [subcutaneous (sc)] obesity, but the …

Central obesity and the accumulation of visceral fat are risk factors for the development of
type 2 diabetes and cardiovascular disease. Omentin is a protein expressed and secreted …

Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of
diabetes worldwide, affecting approximately 4% of the world's adult population. It is …

Obesity is an important cause of morbidity and mortality in developed countries, and is also
becoming increasingly prevalent in the developing world. Although environmental factors …

The role of genetics in obesity is twofold. Studying rare mutations in humans and model
organisms provides fundamental insight into a complex physiological process, and …

Arachidonic (20: 4 (n-6)), eicosapentaenoic (20: 5 (n-3)), and docosahexaenoic (22: 6 (n-3))
acids are major components of brain and retina phospholipids, substrates for eicosanoid …

Diabetes mellitus type 2 is a world-wide growing health problem affecting more than 150
million people at the beginning of the new millennium. It is believed that this number will …

Despite recent advances in the molecular genetics of type 2 diabetes, the majority of
susceptibility genes in humans remain to be identified. We therefore conducted a 10-cM …