Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their
ability to establish lifelong latent infection in neurons. As for all herpesviruses …

Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that
has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA …

Enveloped viruses employ diverse and complex strategies for wrapping at cellular
membranes, many of which are poorly understood. Here, an ultrastructural study of herpes …

Herpes simplex virus (HSV)-1 dramatically alters the architecture and protein composition of
cellular membranes during infection, but its effects upon membrane lipid composition remain …

Membrane-bound transport carriers are used to transfer cargo between membranes of the
secretory and the endocytic pathways. The generation of these carriers can be classified into …

Galectins are unconventionally secreted lectins that participate in the formation of
glycoprotein lattices that perform a variety of cell surface functions. Galectins also bind …

The serine/threonine protein kinase D (PKD) is recruited to the trans-Golgi network (TGN) by
binding diacylglycerol (DAG) and the ARF1 GTPase. PKD, at the TGN, promotes the …

The largest tegument protein of herpes simplex virus type 1 (HSV1), pUL36, is a multivalent
cross-linker between the viral capsids and the tegument and associated membrane proteins …

Hepatitis C virus (HCV) RNA replicates its genome on specialized endoplasmic reticulum
modified membranes termed membranous web and utilizes lipid droplets for initiating the …

Many viruses, enveloped or non-enveloped, remodel host membrane structures for their
replication, assembly and escape from host cells. Herpesviruses are important human …