Click chemistry strategies for the accelerated synthesis of functional macromolecules

Z Geng, JJ Shin, Y Xi, CJ Hawker - Journal of Polymer Science, 2021 - Wiley Online Library
Click chemistry is one of the most powerful strategies for constructing polymeric soft
materials with precise control over architecture and functionality. In this review, we provide a …

Designing smart polymer conjugates for controlled release of payloads

F Seidi, R Jenjob, D Crespy - Chemical reviews, 2018 - ACS Publications
Incorporating labile bonds inside polymer backbone and side chains yields interesting
polymer materials that are responsive to change of environmental stimuli. Drugs can be …

Functional biodegradable polymers via ring-opening polymerization of monomers without protective groups

G Becker, FR Wurm - Chemical society reviews, 2018 - pubs.rsc.org
Biodegradable polymers are of current interest and chemical functionality in such materials
is often demanded in advanced biomedical applications. Functional groups often are not …

Standing on the shoulders of Hermann Staudinger: Post‐polymerization modification from past to present

KA Günay, P Theato, HA Klok - Journal of Polymer Science Part …, 2013 - Wiley Online Library
With a span as long as the history of polymer science itself, post‐polymerization modification
represents a versatile platform for the preparation of diversely functionalized polymers from …

Recent trends in the design of anticancer polymer prodrug nanocarriers

V Delplace, P Couvreur, J Nicolas - Polymer Chemistry, 2014 - pubs.rsc.org
Nanocarriers based on polymers have attracted much attention to perform drug delivery,
especially in cancer therapy. Although significant advances have been reported, important …

Preclinical development of drug delivery systems for paclitaxel-based cancer chemotherapy

F Wang, M Porter, A Konstantopoulos, P Zhang… - Journal of Controlled …, 2017 - Elsevier
Paclitaxel (PTX) is one of the most successful drugs ever used in cancer chemotherapy,
acting against a variety of cancer types. Formulating PTX with Cremophor EL and ethanol …

Smart chemistry in polymeric nanomedicine

R Tong, L Tang, L Ma, C Tu, R Baumgartner… - Chemical Society …, 2014 - pubs.rsc.org
This review provides an overview of smart chemistry developed and utilized in the last 5–10
years in polymer-based drug delivery nanomedicine. Smart chemistry not only facilitates the …

Recent advances in formulation and application of molecular polymer brushes in biomedicine: Therapeutic, diagnostic, and theranostics capabilities

F Adeli, F Abbasi, P Ghandforoushan, HE Külahlı… - Nano Today, 2023 - Elsevier
The applications of nanotechnology in medical sciences, especially in drug and gene
delivery, has experienced unprecedented growth in recent years. The integration of …

Molecular polymer bottlebrushes in nanomedicine: therapeutic and diagnostic applications

M Müllner - Chemical Communications, 2022 - pubs.rsc.org
Molecular polymer bottlebrushes are densely grafted, individual macromolecules with
nanoscale proportions. The last decade has seen an increased focus on this material class …

Poly (lactic acid)-based graft copolymers: Syntheses strategies and improvement of properties for biomedical and environmentally friendly applications: A review

J Coudane, H Van Den Berghe, J Mouton, X Garric… - Molecules, 2022 - mdpi.com
As a potential replacement for petroleum-based plastics, biodegradable bio-based polymers
such as poly (lactic acid)(PLA) have received much attention in recent years. PLA is a …