Fecal microbiota transplantation (FMT) by manual preparation has been applied to treat
diseases for thousands of years. However, this method still endures safety risks and …

Tissue-resident memory T cells (T RM) reside in barrier tissues and provide local immediate
protective immunity. Here, we show that the salivary gland (SG) most-effectively induces …

Human cytomegalovirus (HCMV) is a human pathogen that causes severe disease primarily
in the immunocompromised or immunologically immature individual. To date, no vaccine is …

SARS-CoV-2 antibodies in saliva serve as first line of defense against the virus. They are
present in the mucosa, more precisely in saliva, after a recovered infection and also …

Background An organism's immune response to a vaccine is dependent on a number of
factors, including the site of immunization. While muscle is the most common site for vaccine …

Human cytomegalovirus (HCMV) is the most common congenital infection. Several HCMV
vaccines are in development, but none have yet been approved. An understanding of the …

We investigated the hypothesis that salivary gland inoculation stimulates formation of
ectopic germinal centers (GCs), transforming the gland into a mucosal inductive site …

Human cytomegalovirus (HCMV) is a species-specific β-herpesvirus that infects for life up to
80% of the world's population and causes severe morbidity in at-risk immunocompromised …

As with other herpesviruses, human cytomegalovirus (hCMV) has the ability to establish
lifelong persistence and latent infection following primary exposure, salivary glands (SMGs) …

Background Hemophagocytic lymphohistiocytosis (HLH) is a rare immunological disorder
caused by unbridled activation of T cells and macrophages, culminating in a life-threatening …