Bone turnover markers (BTMs) are used widely, in both research and clinical practice. In the
last 20 years, much experience has been gained in measurement and interpretation of these …

Bone turnover comprises two processes: the removal of old bone (resorption) and the laying
down of new bone (formation). N-terminal propeptide of type I procollagen (PINP) and C …

BACKGROUND Disorders of bone metabolism, most notably osteoporosis, are highly
prevalent and predispose to fractures, causing high patient morbidity and mortality …

Abstract Summary The National Bone Health Alliance (NBHA) recommends standardized
sample handling and patient preparation for C-terminal telopeptide of type I collagen (CTX-I) …

An evidence‐based clinical guideline for the diagnosis and management of Paget's disease
of bone (PDB) was developed using GRADE methodology, by a Guideline Development …

Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by
increased osteoclast-mediated bone resorption and a subsequent compensatory increase in …

Bone turnover markers (BTMs) are divided into the markers of bone formation and those of
bone resorption. N-terminal collagen type I extension propeptide and serum C-terminal …

Measurements of bone markers (BMs) in peripheral blood or urine are a pivotal part of bone
research within modern clinical medicine. In recent years the use of BMs increased …

Adult PD of bone is the second commonest metabolic bone condition after osteoporosis. The
condition is characterized by increased bone cell activity, with bone-resorbing osteoclasts …

Bone fragility fractures remain an important worldwide health and economic problem due to
increased morbidity and mortality. The current methods for predicting fractures are largely …