Motion estimation and correction in SPECT, PET and CT

AZ Kyme, RR Fulton - Physics in Medicine & Biology, 2021 - iopscience.iop.org
Patient motion impacts single photon emission computed tomography (SPECT), positron
emission tomography (PET) and x-ray computed tomography (CT) by giving rise to …

Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

Quantitative rodent brain receptor imaging

K Herfert, JG Mannheim, L Kuebler, S Marciano… - Molecular Imaging and …, 2020 - Springer
Positron emission tomography (PET) is a non-invasive imaging technology employed to
describe metabolic, physiological, and biochemical processes in vivo. These include …

Luminescence thermometry for brain activity monitoring: a perspective

P Rodríguez-Sevilla, R Marin, E Ximendes… - Frontiers in …, 2022 - frontiersin.org
Minimally invasive monitoring of brain activity is essential not only to gain understanding on
the working principles of the brain, but also for the development of new diagnostic tools. In …

A rigid motion correction method for helical computed tomography (CT)

JH Kim, J Nuyts, A Kyme, Z Kuncic… - Physics in Medicine & …, 2015 - iopscience.iop.org
We propose a method to compensate for six degree-of-freedom rigid motion in helical CT of
the head. The method is demonstrated in simulations and in helical scans performed on a …

Markerless motion tracking of awake animals in positron emission tomography

A Kyme, S Se, S Meikle, G Angelis… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
Noninvasive functional imaging of awake, unrestrained small animals using motion-
compensation removes the need for anesthetics and enables an animal's behavioral …

The effect of isoflurane on 18F-FDG uptake in the rat brain: a fully conscious dynamic PET study using motion compensation

MG Spangler-Bickell, B de Laat, R Fulton, G Bormans… - EJNMMI research, 2016 - Springer
Background In preclinical positron emission tomography (PET) studies an anaesthetic is
used to ensure that the animal does not move during the scan. However, anaesthesia may …

Awake 18F-FDG PET imaging of memantine-induced brain activation and test–retest in freely running mice

A Miranda, D Glorie, D Bertoglio… - Journal of Nuclear …, 2019 - Soc Nuclear Med
PET scans of the mouse brain are usually performed with anesthesia to immobilize the
animal. However, it is desirable to avoid the confounding factor of anesthesia in mouse …

Open-field PET: simultaneous brain functional imaging and behavioural response measurements in freely moving small animals

AZ Kyme, GI Angelis, J Eisenhuth, RR Fulton, V Zhou… - Neuroimage, 2019 - Elsevier
A comprehensive understanding of how the brain responds to a changing environment
requires techniques capable of recording functional outputs at the whole-brain level in …

[HTML][HTML] Monte-Carlo simulations and image reconstruction for novel imaging scenarios in emission tomography

JE Gillam, M Rafecas - Nuclear Instruments and Methods in Physics …, 2016 - Elsevier
Emission imaging incorporates both the development of dedicated devices for data
acquisition as well as algorithms for recovering images from that data. Emission tomography …