In-vivo Raman spectroscopy: from basics to applications

E Cordero, I Latka, C Matthäus… - Journal of biomedical …, 2018 - spiedigitallibrary.org
For more than two decades, Raman spectroscopy has found widespread use in biological
and medical applications. The instrumentation and the statistical evaluation procedures …

Label‐free molecular imaging of biological cells and tissues by linear and nonlinear Raman spectroscopic approaches

C Krafft, M Schmitt, IW Schie… - Angewandte Chemie …, 2017 - Wiley Online Library
Raman spectroscopy is an emerging technique in bioanalysis and imaging of biomaterials
owing to its unique capability of generating spectroscopic fingerprints. Imaging cells and …

Developments in spontaneous and coherent Raman scattering microscopic imaging for biomedical applications

C Krafft, IW Schie, T Meyer, M Schmitt… - Chemical Society …, 2016 - pubs.rsc.org
First, the potential role of Raman-based techniques in biomedicine is introduced. Second,
an overview about the instrumentation for spontaneous and coherent Raman scattering …

Portable Raman leaf-clip sensor for rapid detection of plant stress

S Gupta, CH Huang, GP Singh, BS Park, NH Chua… - Scientific Reports, 2020 - nature.com
Precision agriculture requires new technologies for rapid diagnosis of plant stresses, such
as nutrient deficiency and drought, before the onset of visible symptoms and subsequent …

Endoscopic fiber probe for nonlinear spectroscopic imaging

A Lukic, S Dochow, H Bae, G Matz, I Latka… - Optica, 2017 - opg.optica.org
We present a compact multimodal fiber probe that enables the simultaneous recording of
nonlinear imaging modalities like coherent anti-Stokes Raman scattering (CARS), second …

Advances in real‐time fiber‐optic Raman spectroscopy for early cancer diagnosis: Pushing the frontier into clinical endoscopic applications

HPS Heng, C Shu, W Zheng, K Lin… - Translational …, 2021 - Wiley Online Library
Real‐time fiber‐optic Raman spectroscopy has emerged as a compelling approach for
biomedical diagnosis and characterization. This article reviews the following topics related …

Developing fibre optic Raman probes for applications in clinical spectroscopy

O Stevens, IEI Petterson, JCC Day… - Chemical Society Reviews, 2016 - pubs.rsc.org
Raman spectroscopy has been shown by various groups over the last two decades to have
significant capability in discriminating disease states in bodily fluids, cells and tissues …

Mesoscopic fluorescence lifetime imaging: Fundamental principles, clinical applications and future directions

A Alfonso‐Garcia, J Bec, B Weyers… - Journal of …, 2021 - Wiley Online Library
Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …

Raman based molecular imaging and analytics: a magic bullet for biomedical applications!?

TW Bocklitz, S Guo, O Ryabchykov, N Vogler… - Analytical …, 2016 - ACS Publications
The Raman effect was predicted by Schmekal 1 in 1923 and independently discovered in
1928 by two Indian physicists, Raman and Krishna. 2, 3 In principle, monochromatic light is …

Opportunities of optical and spectral technologies in intraoperative histopathology

C Krafft, J Popp - Optica, 2023 - opg.optica.org
Modern optical and spectral technologies represent powerful approaches for a molecular
characterization of tissues enabling delineating pathological tissues but also a label-free …