Infectious diseases and cancer evade immune surveillance using similar mechanisms.
Targeting immune mechanisms using common strategies thus represents a promising …

Research over the past two decades has highlighted that mechanical signaling is a crucial
component in regulating biological processes. Although many processes and proteins are …

Abstract α-Actinins play crucial roles in cytoskeletal mechanobiology by acting as force-
bearing structural modules that orchestrate and sustain the cytoskeletal framework, serving …

The Caenorhabditis elegans HMP-2/HMP-1 complex, akin to the mammalian β-catenin-α-
catenin complex, serves as a critical mechanosensor at cell–cell adherens junctions …

Infrared (IR) spectroscopy stands as a workhorse for exploring bond vibrations, offering a
wealth of chemical insights across diverse frontiers. With increasing focus on the regime of …

It is widely appreciated that double stranded DNA (dsDNA) is subjected to strong and
dynamic mechanical forces in cells. Under increasing tension B-DNA, the most stable …

The organization of nucleosomes into chromatin and their accessibility are shaped by local
DNA mechanics. Conversely, nucleosome positions shape genetic variations, which may …

Investigation of the biological system reveals many underlying principles that govern the
regular life processes. Recently, the analysis of tiny mechanical forces associated with many …

Understanding cellular force transmission dynamics is crucial in mechanobiology. We
developed the DNA-based ForceChrono probe to measure force magnitude, duration, and …

Extracellular vesicles (EVs), secreted from most cells, are small lipid membranes of vesicles
of 30 to 1000 nm in diameter and contain nucleic acids, proteins, and intracellular …