Bottom-up tissue engineering

DL Elbert - Current opinion in biotechnology, 2011 - Elsevier
Recapitulating the elegant structures formed during development is an extreme synthetic
and biological challenge. Great progress has been made in developing materials to support …

Controlling structure with injectable biomaterials to better mimic tissue heterogeneity and anisotropy

S Babu, F Albertino, A Omidinia Anarkoli… - Advanced …, 2021 - Wiley Online Library
Tissue regeneration of sensitive tissues calls for injectable scaffolds, which are minimally
invasive and offer minimal damage to the native tissues. However, most of these systems …

Enzyme-responsive hydrogel microparticles for pulmonary drug delivery

E Secret, SJ Kelly, KE Crannell… - ACS applied materials & …, 2014 - ACS Publications
Poly (ethylene glycol) based hydrogel microparticles were developed for pulmonary drug
delivery. Hydrogels are particularly attractive for pulmonary delivery because they can be …

Novel multifunctional NaYF4: Er 3+, Yb 3+/PEGDA hybrid microspheres: NIR-light-activated photopolymerization and drug delivery

Q Xiao, Y Ji, Z Xiao, Y Zhang, H Lin… - Chemical …, 2013 - pubs.rsc.org
By utilizing multicolor upconversion luminescence of rare earth-doped nanophosphors
(UCNPs), NIR-light-activated photopolymerization and controlled drug delivery is achieved …

Superadsorbent with three-dimensional networks: From bulk hydrogel to granular hydrogel

Y Zheng, A Wang - European Polymer Journal, 2015 - Elsevier
Hydrogels are 3D networks of polymer chains that are crosslinked via either physical or
chemical bonds. A strong repulsive force is generated among those abundant functional …

Methods for generating hydrogel particles for protein delivery

AL Liu, AJ García - Annals of biomedical engineering, 2016 - Springer
Proteins represent a major class of therapeutic molecules with vast potential for the
treatment of acute and chronic diseases and regenerative medicine applications. Hydrogels …

Synthesis of architecturally well-defined nanogels via RAFT polymerization for potential bioapplications

Z An, Q Qiu, G Liu - Chemical Communications, 2011 - pubs.rsc.org
Nanogel synthesis by RAFT polymerization is an emerging field for the control of
architectures and functions of polymeric nanomaterials for bioapplications. In this Feature …

Facile microfluidic fabrication of biocompatible hydrogel microspheres in a novel microfluidic device

M Chen, R Aluunmani, G Bolognesi, GT Vladisavljević - Molecules, 2022 - mdpi.com
Poly (ethylene glycol) diacrylate (PEGDA) microgels with tuneable size and porosity find
applications as extracellular matrix mimics for tissue-engineering scaffolds, biosensors, and …

Tuning the Mechanical Properties of Poly (Ethylene Glycol) Microgel‐Based Scaffolds to Increase 3D Schwann Cell Proliferation

W Zhou, JM Stukel, HL Cebull… - Macromolecular …, 2016 - Wiley Online Library
2D in vitro studies have demonstrated that Schwann cells prefer scaffolds with mechanical
modulus approximately 10× higher than the modulus preferred by nerves, limiting the ability …

Modification of agarose with carboxylation and grafting dopamine for promotion of its cell-adhesiveness

S Yixue, C Bin, G Yuan, W Chaoxi, Z Lingmin… - Carbohydrate …, 2013 - Elsevier
In order to improve bioactivity of agarose, we modified agarose by carboxylation and grafting
dopamine. Under alkaline condition, carboxylated agarose was prepared using 2, 2, 6, 6 …