Cytosolic Ca 2+ concentration levels fluctuate in an ordered manner along the cell cycle, in
line with the fact that Ca 2+ is involved in the regulation of cell proliferation. Cell proliferation …

Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …

Ovarian cancer (OC) is the most lethal gynecological malignancy due to tumor
heterogeneity, the lack of reliable early diagnosis methods and the high incidence of …

Glioblastoma multiforme (GBM) is one of the most lethal forms of cancer in humans, with a
median survival of 10 to 12 months. Glioblastoma is highly malignant since the cells are …

Mechanisms underlying therapy resistance of tumor cells include protein kinase Akt.
Putative Akt targets include store-operated Ca 2+-entry (SOCE) accomplished by pore …

Epithelial Ovarian cancer (EOC) is the deadliest gynecologic malignancy and represents the
fifth leading cause of all cancer-related deaths in women. The majority of patients are …

Chondroitin sulfate (CS)-calcium complex (CSCa) was fabricated, and the structural
characteristics of CSCa and its proliferative bioactivity to the chondrocyte were investigated …

Cancer is a main public health problem all over the world. It affects millions of humans no
matter their age, gender, education, or social status. Although chemotherapy is the main …

Evidence for a role for calcium channel proteins in cell proliferation is numerous suggesting
that calcium influx is essential in this physiological process. Several studies in the past thirty …

The development of nanomaterials for stable, controlled delivery of drugs and efficient
suppression of tumor growth with desirable biosafety remains challenging in the nano …