Long noncoding RNA and cancer: a new paradigm

A Bhan, M Soleimani, SS Mandal - Cancer research, 2017 - AACR
In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

LncRNAs as potential diagnostic and prognostic biomarkers in gastric cancer: a novel approach to personalized medicine

S Fattahi, M Kosari‐Monfared… - Journal of cellular …, 2020 - Wiley Online Library
Gastric cancer is the third leading cause of cancer death with 5‐year survival rate of about
30–35%. Since early detection is associated with decreased mortality, identification of novel …

[HTML][HTML] Expression of the long non-coding RNA HOTAIR correlates with disease progression in bladder cancer and is contained in bladder cancer patient urinary …

C Berrondo, J Flax, V Kucherov, A Siebert, T Osinski… - PloS one, 2016 - journals.plos.org
Exosomes are 30-150nM membrane-bound secreted vesicles that are readily isolated from
biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA) …

[HTML][HTML] Salivary HOTAIR and PVT1 as novel biomarkers for early pancreatic cancer

Z Xie, X Chen, J Li, Y Guo, H Li, X Pan, J Jiang, H Liu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Sensitive and non-invasive biomarkers for pancreatic cancer (PC) are lacking. We aimed to
identify salivary long non-coding RNAs (lncRNAs) as biomarkers in diagnosis of resectable …

The emerging roles of long noncoding RNA ROR (lincRNA-ROR) and its possible mechanisms in human cancers

Y Pan, C Li, J Chen, K Zhang, X Chu, R Wang… - Cellular physiology and …, 2016 - karger.com
To date, there is only up to 2% of protein-coding genes that are stably transcribed, whereas
the vast majority are non-coding RNAs (ncRNAs). These ncRNAs, also known as non …

[HTML][HTML] Potential applications of MEG3 in cancer diagnosis and prognosis

Y He, Y Luo, B Liang, L Ye, G Lu, W He - Oncotarget, 2017 - ncbi.nlm.nih.gov
LncRNAs are emerging as integral functional and regulatory components of normal
biological activities and are now considered as critically involved in the development of …

Long noncoding RNAs and tumorigenesis: genetic associations, molecular mechanisms, and therapeutic strategies

F Zhang, L Zhang, C Zhang - Tumor Biology, 2016 - Springer
The human genome contains a large number of nonprotein-coding sequences. Recently,
new discoveries in the functions of nonprotein-coding sequences have demonstrated that …

[HTML][HTML] Novel LncRNA OXCT1-AS1 indicates poor prognosis and contributes to tumorigenesis by regulating miR-195/CDC25A axis in glioblastoma

C Zhong, Q Yu, Y Peng, S Zhou, Z Liu, Y Deng… - Journal of Experimental …, 2021 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) contribute to multiple biological
processes in human glioblastoma (GBM). However, identifying a specific lncRNA target …

[HTML][HTML] The role of long non-coding RNAs (lncRNAs) in female oriented cancers

F Naz, I Tariq, S Ali, A Somaida, E Preis, U Bakowsky - Cancers, 2021 - mdpi.com
Simple Summary Breast and gynecological cancers, broadly termed as female-oriented
cancers, are the primary cause of death among females in developed and developing …

The “good-cop bad-cop” TGF-beta role in breast cancer modulated by non-coding RNAs

D Gulei, N Mehterov, H Ling, G Stanta, C Braicu… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Lack of early diagnosis methods and the development of drug resistance are
among the main reasons for increased mortality rates within breast cancer patients. These …