Treatment strategies for infected wounds

I Negut, V Grumezescu, AM Grumezescu - Molecules, 2018 - mdpi.com
The treatment of skin wounds is a key research domain owing to the important functional
and aesthetic role of this tissue. When the skin is impaired, bacteria can soon infiltrate into …

Nanomaterials for wound healing and infection control

MM Mihai, MB Dima, B Dima, AM Holban - Materials, 2019 - mdpi.com
Wound healing has been intensely studied in order to develop an “ideal” technique that
achieves expeditious recovery and reduces scarring to the minimum, thus ensuring function …

ZnO nanoparticles-modified dressings to inhibit wound pathogens

SMI Rayyif, HB Mohammed, C Curuțiu, AC Bîrcă… - Materials, 2021 - mdpi.com
Zinc oxide (ZnO) nanoparticles (NPs) have been investigated for various skin therapies in
recent years. These NPs can improve the healing and modulate inflammation in the wounds …

Chitosan-Coated PLGA Nanoparticles Loaded with Peganum harmala Alkaloids with Promising Antibacterial and Wound Healing Activities

HMES Azzazy, SA Fahmy, NK Mahdy, MR Meselhy… - Nanomaterials, 2021 - mdpi.com
Wound healing is a major healthcare concern, and complicated wounds may lead to severe
outcomes such as septicemia and amputations. To date, management choices are limited …

Repair Process Impairment by Pseudomonas aeruginosa in Epithelial Tissues: Major Features and Potential Therapeutic Avenues

M Ruffin, E Brochiero - Frontiers in cellular and infection microbiology, 2019 - frontiersin.org
Epithelial tissues protecting organs from the environment are the first-line of defense against
pathogens. Therefore, efficient repair mechanisms after injury are crucial to maintain …

Silver nanoparticles and its mechanistic insight for chronic wound healing: review on recent progress

M Singh, V Thakur, V Kumar, M Raj, S Gupta, N Devi… - Molecules, 2022 - mdpi.com
Wounds are structural and functional disruptions of skin that occur because of trauma,
surgery, acute illness, or chronic disease conditions. Chronic wounds are caused by a …

Nanocoatings for chronic wound repair—modulation of microbial colonization and biofilm formation

MM Mihai, M Preda, I Lungu, MC Gestal… - International journal of …, 2018 - mdpi.com
Wound healing involves a complex interaction between immunity and other natural host
processes, and to succeed it requires a well-defined cascade of events. Chronic wound …

Current concepts on Pseudomonas aeruginosa interaction with human airway epithelium

A Muggeo, C Coraux, T Guillard - PLoS pathogens, 2023 - journals.plos.org
Pseudomonas aeruginosa is a major, but opportunistic, respiratory pathogen, which rarely
infects healthy individuals, mainly due to the barrier effect of the human airway epithelium …

Chronic wounds: innovations in diagnostics and therapeutics

M Haalboom - Current medicinal chemistry, 2018 - ingentaconnect.com
Background: A major global health issue is the existence of chronic wounds. Appropriate
diagnosis and treatment is essential to promote wound healing and prevent further …

Microbial biofilms: impact on the pathogenesis of periodontitis, cystic fibrosis, chronic wounds and medical device-related infections

M Madalina Mihai, A Maria Holban… - Current topics in …, 2015 - ingentaconnect.com
The majority of chronic infections are associated with mono-or polymicrobial biofilms, having
a significant impact on the patients' quality of life and survival rates. Although the use of …