Pharmaceutical nanotechnology: from the bench to the market

ZM Mazayen, AM Ghoneim, RS Elbatanony… - Future journal of …, 2022 - Springer
Background Nanotechnology is considered a new and rapidly emerging area in the
pharmaceutical and medicinal field. Nanoparticles, as drug delivery systems, impart several …

Tailoring the multi-functional properties of phospholipids for simple to complex self-assemblies

T Waghule, RN Saha, A Alexander, G Singhvi - Journal of Controlled …, 2022 - Elsevier
The unique interfacial properties, huge diversity, and biocompatible nature of phospholipids
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …

Fundamental aspects of lipid-based excipients in lipid-based product development

D Nakmode, V Bhavana, P Thakor, J Madan, PK Singh… - Pharmaceutics, 2022 - mdpi.com
Poor aqueous solubility of drugs is still a foremost challenge in pharmaceutical product
development. The use of lipids in designing formulations provides an opportunity to …

Smart nanocarriers-based drug delivery for cancer therapy: An innovative and developing strategy

S Huda, MA Alam, PK Sharma - Journal of Drug Delivery Science and …, 2020 - Elsevier
Cancer is one of the leading causes of death but is surpassed by cardiovascular diseases.
Cancer is a disease categorized by the uncontrolled growth of cells worldwide with an …

Nanoformulation strategies for improving intestinal permeability of drugs: A more precise look at permeability assessment methods and pharmacokinetic properties …

D Babadi, S Dadashzadeh, M Osouli… - Journal of controlled …, 2020 - Elsevier
The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …

Design of temozolomide-loaded proliposomes and lipid crystal nanoparticles with industrial feasible approaches: comparative assessment of drug loading …

T Waghule, VK Rapalli, G Singhvi… - Journal of liposome …, 2021 - Taylor & Francis
Temozolomide is a drug approved for treating glioblastomas, which has 100% oral
bioavailability but gets degraded at physiological pH thus having very short half-life and only …

Nanostructured polymeric, liposomal and other materials to control the drug delivery for cardiovascular diseases

D Skourtis, D Stavroulaki, V Athanasiou, PG Fragouli… - Pharmaceutics, 2020 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of death globally, taking an
estimated 17.9 million lives each year, representing one third of global mortality. As existing …

Effects of micro-environmental pH of liposome on chemical stability of loaded drug

XR Shao, XQ Wei, S Zhang, N Fu, YF Lin… - Nanoscale research …, 2017 - Springer
Liposome is a promising carrier system for delivering bioactive molecules. However, the
successful delivery of pH-sensitive molecules is still limited by the intrinsic instability of …

Novel drug delivery systems

AM Faheem, DH Abdelkader - Engineering drug delivery systems, 2020 - Elsevier
The field of nanomedicine employs novel drug delivery systems (NDDSs) to overcome the
limitations of traditional dosage forms. Conventional formulations are associated with poor …

Anticancer activities of phytoconstituents and their liposomal targeting strategies against tumor cells and the microenvironment

J Zhang, X Li, L Huang - Advanced drug delivery reviews, 2020 - Elsevier
Various bioactive ingredients have been extracted from Chinese herbal medicines (CHMs)
that affect tumor progression and metastasis. To further understand the mechanisms of …