Pharmaceutical nanotechnology: from the bench to the market
Background Nanotechnology is considered a new and rapidly emerging area in the
pharmaceutical and medicinal field. Nanoparticles, as drug delivery systems, impart several …
pharmaceutical and medicinal field. Nanoparticles, as drug delivery systems, impart several …
Tailoring the multi-functional properties of phospholipids for simple to complex self-assemblies
T Waghule, RN Saha, A Alexander, G Singhvi - Journal of Controlled …, 2022 - Elsevier
The unique interfacial properties, huge diversity, and biocompatible nature of phospholipids
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …
Fundamental aspects of lipid-based excipients in lipid-based product development
Poor aqueous solubility of drugs is still a foremost challenge in pharmaceutical product
development. The use of lipids in designing formulations provides an opportunity to …
development. The use of lipids in designing formulations provides an opportunity to …
Smart nanocarriers-based drug delivery for cancer therapy: An innovative and developing strategy
S Huda, MA Alam, PK Sharma - Journal of Drug Delivery Science and …, 2020 - Elsevier
Cancer is one of the leading causes of death but is surpassed by cardiovascular diseases.
Cancer is a disease categorized by the uncontrolled growth of cells worldwide with an …
Cancer is a disease categorized by the uncontrolled growth of cells worldwide with an …
Nanoformulation strategies for improving intestinal permeability of drugs: A more precise look at permeability assessment methods and pharmacokinetic properties …
The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …
Design of temozolomide-loaded proliposomes and lipid crystal nanoparticles with industrial feasible approaches: comparative assessment of drug loading …
T Waghule, VK Rapalli, G Singhvi… - Journal of liposome …, 2021 - Taylor & Francis
Temozolomide is a drug approved for treating glioblastomas, which has 100% oral
bioavailability but gets degraded at physiological pH thus having very short half-life and only …
bioavailability but gets degraded at physiological pH thus having very short half-life and only …
Nanostructured polymeric, liposomal and other materials to control the drug delivery for cardiovascular diseases
D Skourtis, D Stavroulaki, V Athanasiou, PG Fragouli… - Pharmaceutics, 2020 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of death globally, taking an
estimated 17.9 million lives each year, representing one third of global mortality. As existing …
estimated 17.9 million lives each year, representing one third of global mortality. As existing …
Effects of micro-environmental pH of liposome on chemical stability of loaded drug
XR Shao, XQ Wei, S Zhang, N Fu, YF Lin… - Nanoscale research …, 2017 - Springer
Liposome is a promising carrier system for delivering bioactive molecules. However, the
successful delivery of pH-sensitive molecules is still limited by the intrinsic instability of …
successful delivery of pH-sensitive molecules is still limited by the intrinsic instability of …
Novel drug delivery systems
AM Faheem, DH Abdelkader - Engineering drug delivery systems, 2020 - Elsevier
The field of nanomedicine employs novel drug delivery systems (NDDSs) to overcome the
limitations of traditional dosage forms. Conventional formulations are associated with poor …
limitations of traditional dosage forms. Conventional formulations are associated with poor …
Anticancer activities of phytoconstituents and their liposomal targeting strategies against tumor cells and the microenvironment
Various bioactive ingredients have been extracted from Chinese herbal medicines (CHMs)
that affect tumor progression and metastasis. To further understand the mechanisms of …
that affect tumor progression and metastasis. To further understand the mechanisms of …