Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …

The antiporter system xc− imports the amino acid cystine, the oxidized form of cysteine, into
cells with a 1: 1 counter-transport of glutamate. It is composed of a light chain, xCT, and a …

Since a high intake of fruits and vegetables is inversely related to the incidence of several
degenerative diseases, the importance of a balanced diet in relation to human health has …

Neuronal dysfunction initiates several intracellular signaling cascades to release different
proinflammatory cytokines and chemokines, as well as various reactive oxygen species. In …

Significance: Diet-derived antioxidants are now being increasingly investigated for their
health-promoting effects, including their role in the chemoprevention of cancer. In general …

Ischemic stroke is a challenging disease with high mortality and disability rates, causing a
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …

Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …

Neurodegenerative disorders pose a significant health burden and imprint a debilitative
impact on the quality of life. Importantly, aging is intricately intertwined with the progression …

Current evidence indicates that the consumption of strawberries, a natural source of a wide
range of nutritive and bioactive compounds, is associated with the prevention and …