[HTML][HTML] Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

TM Uddin, AJ Chakraborty, A Khusro… - Journal of infection and …, 2021 - Elsevier
Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-
molecular-weight bioactive agents have also been used for a variety of other medicinal …

Sulfonamide drugs: Structure, antibacterial property, toxicity, and biophysical interactions

A Ovung, J Bhattacharyya - Biophysical reviews, 2021 - Springer
Sulfonamide (or sulphonamide) functional group chemistry (SN) forms the basis of several
groups of drug. In vivo sulfonamides exhibit a range of pharmacological activities, such as …

[HTML][HTML] Review on multiple facets of drug resistance: a rising challenge in the 21st century

M Saha, A Sarkar - Journal of xenobiotics, 2021 - mdpi.com
With the advancements of science, antibiotics have emerged as an amazing gift to the
human and animal healthcare sectors for the treatment of bacterial infections and other …

[HTML][HTML] Actinomycetes: A Never-Ending Source of Bioactive Compounds—An Overview on Antibiotics Production

D De Simeis, S Serra - Antibiotics, 2021 - mdpi.com
The discovery of penicillin by Sir Alexander Fleming in 1928 provided us with access to a
new class of compounds useful at fighting bacterial infections: antibiotics. Ever since, a …

[HTML][HTML] Polymeric nanoparticles for antimicrobial therapies: An up-to-date overview

VA Spirescu, C Chircov, AM Grumezescu… - Polymers, 2021 - mdpi.com
Despite the many advancements in the pharmaceutical and medical fields and the
development of numerous antimicrobial drugs aimed to suppress and destroy pathogenic …

[HTML][HTML] Enterotoxigenic Escherichia coli infection of weaned pigs: Intestinal challenges and nutritional intervention to enhance disease resistance

K Kim, M Song, Y Liu, P Ji - Frontiers in immunology, 2022 - frontiersin.org
Enterotoxigenic Escherichia coli (ETEC) infection induced post-weaning diarrhea is one of
the leading causes of morbidity and mortality in newly weaned pigs and one of the …

An overlooked and underrated endemic mycosis—Talaromycosis and the pathogenic fungus Talaromyces marneffei

F Wang, RH Han, S Chen - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …

[HTML][HTML] Bacterial Targets of Antibiotics in Methicillin-Resistant Staphylococcus aureus

H Lade, JS Kim - Antibiotics, 2021 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent bacterial
pathogens and continues to be a leading cause of morbidity and mortality worldwide. MRSA …

[PDF][PDF] Mechanisms of antibiotics resistance in bacteria

TH Hasan, RA Al-Harmoosh - Sys Rev Pharm, 2020 - researchgate.net
The resistance is determining a growing hug issue in health fields worldwide, where the
bacterial cells possessed the ability to resist the old antibiotics as well as the newly …

[HTML][HTML] Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

J Reader, ME van der Watt, D Taylor… - Nature …, 2021 - nature.com
Chemical matter is needed to target the divergent biology associated with the different life
cycle stages of Plasmodium. Here, we report the parallel de novo screening of the …