The primary cilium is an antenna-like, immotile organelle present on most types of
mammalian cells, which interprets extracellular signals that regulate growth and …

The cilium, once considered a vestigial structure, is a conserved, microtubule-based
organelle critical for transducing extracellular chemical and mechanical signals that control …

The life cycle of a primary cilium begins in quiescence and ends prior to mitosis. In quiescent
cells, the primary cilium insulates itself from contiguous dynamic membrane processes on …

The primary cilium is an antenna-like organelle assembled on most types of quiescent and
differentiated mammalian cells. This immotile structure is essential for interpreting …

Although tumours initiate from oncogenic changes in a cancer cell, subsequent tumour
progression and therapeutic response depend on interactions between the cancer cells and …

Primary cilia are solitary, microtubule-based structures emanating from the surface of most
vertebrate cells. Although it is understood that ciliary assembly and disassembly both …

Primary cilia, microtubule-based sensory structures, orchestrate various critical signals
during development and tissue homeostasis. In view of the rising interest into the reciprocal …

The primary cilium is a ubiquitous microtubule-based organelle that senses external
environment and modulates diverse signaling pathways in different cell types and tissues …

Appropriate axonal growth and connectivity are essential for functional wiring of the brain.
Joubert syndrome-related disorders (JSRD), a group of ciliopathies in which mutations …

The primary cilium is a central signaling hub in cell proliferation and differentiation and is
built and disassembled every cell cycle in many animal cells. Disassembly is critically …