[HTML][HTML] Targeting macrophages in cancer immunotherapy
Z Duan, Y Luo - Signal transduction and targeted therapy, 2021 - nature.com
Immunotherapy is regarded as the most promising treatment for cancers. Various cancer
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …
[HTML][HTML] Application of exosomes as liquid biopsy in clinical diagnosis
B Zhou, K Xu, X Zheng, T Chen, J Wang… - Signal transduction and …, 2020 - nature.com
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
[HTML][HTML] Exosome-based immunotherapy: a promising approach for cancer treatment
Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …
in the application of cell-released small vesicles that stimulate the immune system. As cell …
[HTML][HTML] Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment
Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
Cancer-derived exosomes: their role in cancer biology and biomarker development
VC Kok, CC Yu - International Journal of Nanomedicine, 2020 - Taylor & Francis
Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …
present in all body fluids. They are produced actively in tumor cells, which are released and …
[HTML][HTML] Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer
Abstract Background 5-Fluorouracil (5-FU) has been commonly prescribed for patients with
colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in …
colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in …
[HTML][HTML] Exosome-mediated metastasis: communication from a distance
Metastasis, a critical phase of tumor progression, remains a primary challenge in treating
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …
Extracellular vesicles in cancer—implications for future improvements in cancer care
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …
cell–cell communication within complex tissue environments. Such communication …
[HTML][HTML] The drug-resistance mechanisms of five platinum-based antitumor agents
J Zhou, Y Kang, L Chen, H Wang, J Liu… - Frontiers in …, 2020 - frontiersin.org
Platinum-based anticancer drugs, including cisplatin, carboplatin, oxaliplatin, nedaplatin,
and lobaplatin, are heavily applied in chemotherapy regimens. However, the intrinsic or …
and lobaplatin, are heavily applied in chemotherapy regimens. However, the intrinsic or …
Monocytes in the tumor microenvironment
S Ugel, S Canè, F De Sanctis… - Annual Review of …, 2021 - annualreviews.org
Immunotherapy has revolutionized cancer treatment over the past decade. Nonetheless,
prolonged survival is limited to relatively few patients. Cancers enforce a multifaceted …
prolonged survival is limited to relatively few patients. Cancers enforce a multifaceted …