The aging navigational system
The discovery of neuronal systems dedicated to computing spatial information, composed of
functionally distinct cell types such as place and grid cells, combined with an extensive body …
functionally distinct cell types such as place and grid cells, combined with an extensive body …
Integrating new findings and examining clinical applications of pattern separation
Pattern separation, the ability to independently represent and store similar experiences, is a
crucial facet of episodic memory. Growing evidence suggests that the hippocampus …
crucial facet of episodic memory. Growing evidence suggests that the hippocampus …
The human dentate gyrus plays a necessary role in discriminating new memories
Our day-to-day experiences are often similar to one another, occurring in the same place at
the same time of day, with common people and objects, and with a shared purpose. Humans …
the same time of day, with common people and objects, and with a shared purpose. Humans …
[HTML][HTML] Age-related functional changes in domain-specific medial temporal lobe pathways
There is now converging evidence from studies in animals and humans that the medial
temporal lobes (MTLs) harbor anatomically distinct processing pathways for object and …
temporal lobes (MTLs) harbor anatomically distinct processing pathways for object and …
Memory reactivation during learning simultaneously promotes dentate gyrus/CA2, 3 pattern differentiation and CA1 memory integration
RJ Molitor, KR Sherrill, NW Morton… - Journal of …, 2021 - Soc Neuroscience
Events that overlap with previous experience may trigger reactivation of existing memories.
However, such reactivation may have different representational consequences within the …
However, such reactivation may have different representational consequences within the …
Ageing-and dementia-friendly design: theory and evidence from cognitive psychology, neuropsychology and environmental psychology can contribute to design …
JM Wiener, F Pazzaglia - Cognitive processing, 2021 - Springer
Many older people, both with and without dementia, eventually move from their familiar
home environments into unfamiliar surroundings, such as sheltered housing or care homes …
home environments into unfamiliar surroundings, such as sheltered housing or care homes …
Eye movements support behavioral pattern completion
The ability to recall a detailed event from a simple reminder is supported by pattern
completion, a cognitive operation performed by the hippocampus wherein existing …
completion, a cognitive operation performed by the hippocampus wherein existing …
Development of holistic episodic recollection
Episodic memory binds the diverse elements of an event into a coherent representation.
This coherence allows for the reconstruction of different aspects of an experience when …
This coherence allows for the reconstruction of different aspects of an experience when …
Tests of pattern separation and pattern completion in humans—A systematic review
To systematically review the characteristics, validity and outcome measures of tasks that
have been described in the literature as assessing pattern separation and pattern …
have been described in the literature as assessing pattern separation and pattern …
Pattern separation and pattern completion: Behaviorally separable processes?
Episodic memory capacity requires several processes, including mnemonic discrimination of
similar experiences, termed pattern separation, and holistic retrieval of multidimensional …
similar experiences, termed pattern separation, and holistic retrieval of multidimensional …