[HTML][HTML] STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications
I Tošić, DA Frank - Neoplasia, 2021 - Elsevier
The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3)
is activated constitutively in a wide array of human cancers. It is an appealing molecular …
is activated constitutively in a wide array of human cancers. It is an appealing molecular …
Artificial intelligence to decode cancer mechanism: beyond patient stratification for precision oncology
The multitude of multi-omics data generated cost-effectively using advanced high-
throughput technologies has imposed challenging domain for research in Artificial …
throughput technologies has imposed challenging domain for research in Artificial …
Ultrabright and highly polarity‐sensitive NIR‐I/NIR‐II fluorophores for the tracking of lipid droplets and staging of fatty liver disease
X Zhou, K Zhang, C Yang, Y Pei, L Zhao… - Advanced Functional …, 2022 - Wiley Online Library
Visualizing the progression of fatty liver disease in vivo is of great significance in biomedical
research of fatty liver, but hindered by the lack of suitable approaches with deep penetration …
research of fatty liver, but hindered by the lack of suitable approaches with deep penetration …
Phasor S-FLIM: a new paradigm for fast and robust spectral fluorescence lifetime imaging
Fluorescence lifetime imaging microscopy (FLIM) and spectral imaging are two broadly
applied methods for increasing dimensionality in microscopy. However, their combination is …
applied methods for increasing dimensionality in microscopy. However, their combination is …
Enhancing ductal carcinoma classification using transfer learning with 3D U-net models in breast cancer imaging
Breast cancer ranks among the leading causes of death for women globally, making it
imperative to swiftly and precisely detect the condition to ensure timely treatment and …
imperative to swiftly and precisely detect the condition to ensure timely treatment and …
Mass spectrometry imaging revealed alterations of lipid metabolites in multicellular tumor spheroids in response to hydroxychloroquine
Y Chen, T Wang, P Xie, Y Song, J Wang, Z Cai - Analytica chimica acta, 2021 - Elsevier
Abstract Three-dimensional (3D) multicellular tumor spheroids (MCTS) that mimic the
complex tumor microenvironment provide a good platform for in vitro study of drug and …
complex tumor microenvironment provide a good platform for in vitro study of drug and …
Nanocomposite scaffolds for monitoring of drug diffusion in three-dimensional cell environments by surface-enhanced Raman spectroscopy
J Plou, B Molina-Martínez, C García-Astrain… - Nano Letters, 2021 - ACS Publications
Monitoring dynamic processes in complex cellular environments requires the integration of
uniformly distributed detectors within such three-dimensional (3D) networks, to an extent that …
uniformly distributed detectors within such three-dimensional (3D) networks, to an extent that …
Lipidomic comparison of 2D and 3D colon cancer cell culture models
F Tobias, AB Hummon - Journal of Mass Spectrometry, 2022 - Wiley Online Library
Altered lipid metabolism is one of the hallmarks of cancer. Cellular proliferation and de novo
synthesis of lipids are related to cancer progression. In this study, we evaluated the lipidomic …
synthesis of lipids are related to cancer progression. In this study, we evaluated the lipidomic …
Spatial metabolomics and lipidomics reveal the mechanisms of the enhanced growth of breast cancer cell spheroids exposed to triclosan
J Chen, P Xie, P Wu, Z Lin, Y He… - Environmental Science & …, 2023 - ACS Publications
Triclosan (TCS), an antimicrobial compound, is known to have potential endocrine-
disruptive properties, but the underlying toxic mechanisms at the metabolic level are not well …
disruptive properties, but the underlying toxic mechanisms at the metabolic level are not well …
Spatial-omics technologies: the new enterprise in 3D breast cancer models
The fields of tissue bioengineering,-omics, and spatial biology are advancing rapidly, each
offering the opportunity for a paradigm shift in breast cancer research. However, to date …
offering the opportunity for a paradigm shift in breast cancer research. However, to date …