[HTML][HTML] Controlling vector-borne diseases by releasing modified mosquitoes

HA Flores, SL O'Neill - Nature Reviews Microbiology, 2018 - nature.com
Aedes mosquito-transmitted diseases, such as dengue, Zika and chikungunya, are
becoming major global health emergencies while old threats, such as yellow fever, are re …

Aedes aegypti and Ae. albopictus microbiome/virome: new strategies for controlling arboviral transmission?

M Gómez, D Martinez, M Muñoz, JD Ramírez - Parasites & vectors, 2022 - Springer
Abstract Abstract Aedes aegypti and Aedes albopictus are the main vectors of highly
pathogenic viruses for humans, such as dengue (DENV), chikungunya (CHIKV), and Zika …

Wolbachia as translational science: controlling mosquito-borne pathogens

EP Caragata, HLC Dutra, PHF Sucupira… - Trends in …, 2021 - cell.com
In this review we examine how exploiting the Wolbachia–mosquito relationship has become
an increasingly popular strategy for controlling arbovirus transmission. Field deployments of …

Japanese encephalitis virus interaction with mosquitoes: A review of vector competence, vector capacity and mosquito immunity

C Van den Eynde, C Sohier, S Matthijs, N De Regge - Pathogens, 2022 - mdpi.com
Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic flavivirus and a major cause
of human viral encephalitis in Asia. We provide an overview of the knowledge on vector …

The bacterium Wolbachia exploits host innate immunity to establish a symbiotic relationship with the dengue vector mosquito Aedes aegypti

X Pan, A Pike, D Joshi, G Bian, MJ McFadden… - The ISME …, 2018 - academic.oup.com
A host's immune system plays a central role in shaping the composition of the microbiota
and, in return, resident microbes influence immune responses. Symbiotic associations of the …

Wolbachia-Virus interactions and arbovirus control through population replacement in mosquitoes

TH Ant, MV Mancini, CJ McNamara… - … and Global Health, 2023 - Taylor & Francis
Following transfer into the primary arbovirus vector Aedes aegypti, several strains of the
intracellular bacterium Wolbachia have been shown to inhibit the transmission of dengue …

[HTML][HTML] Dual Insect specific virus infection limits Arbovirus replication in Aedes mosquito cells

MJ Schultz, HM Frydman, JH Connor - Virology, 2018 - Elsevier
Aedes mosquitoes are vectors for many pathogenic viruses. Cell culture systems facilitate
the investigation of virus growth in the mosquito vector. We found Zika virus (ZIKV) growth to …

Insulin potentiates JAK/STAT signaling to broadly inhibit flavivirus replication in insect vectors

LRH Ahlers, CE Trammell, GF Carrell, S Mackinnon… - Cell reports, 2019 - cell.com
Summary The World Health Organization estimates that more than half of the world's
population is at risk for vector-borne diseases, including arboviruses. Because many …

Vector specificity of arbovirus transmission

M Viglietta, R Bellone, AA Blisnick… - Frontiers in …, 2021 - frontiersin.org
More than 25% of human infectious diseases are vector-borne diseases (VBDs). These
diseases, caused by pathogens shared between animals and humans, are a growing threat …

Conflict in the Intracellular Lives of Endosymbionts and Viruses: A Mechanistic Look at Wolbachia-Mediated Pathogen-blocking

ARI Lindsey, T Bhattacharya, ILG Newton, RW Hardy - Viruses, 2018 - mdpi.com
At the forefront of vector control efforts are strategies that leverage host-microbe associations
to reduce vectorial capacity. The most promising of these efforts employs Wolbachia, a …