[HTML][HTML] Epigenetic biomarkers in gastrointestinal cancers: The current state and clinical perspectives
HM Vedeld, A Goel, GE Lind - Seminars in cancer biology, 2018 - Elsevier
Abstract Each year, almost 4.1 million people are diagnosed with gastrointestinal (GI)
cancers. Due to late detection of this disease, the mortality is high, causing approximately 3 …
cancers. Due to late detection of this disease, the mortality is high, causing approximately 3 …
Fusobacterium nucleatumin Colorectal Carcinoma Tissue According to Tumor Location
OBJECTIVES: Evidence suggests a possible role ofFusobacterium nucleatumin colorectal
carcinogenesis, especially in right-sided proximal colorectum. Considering a change in …
carcinogenesis, especially in right-sided proximal colorectum. Considering a change in …
[HTML][HTML] Clinical, pathological, and molecular characteristics of CpG island methylator phenotype in colorectal cancer: a systematic review and meta-analysis
BACKGROUND: CpG island methylator phenotype (CIMP) tumors, comprising 20% of
colorectal cancers, are associated with female sex, age, right-sided location, and BRAF …
colorectal cancers, are associated with female sex, age, right-sided location, and BRAF …
BRAF Mutation in Colorectal Cancers: From Prognostic Marker to Targetable Mutation
I Nakayama, T Hirota, E Shinozaki - Cancers, 2020 - mdpi.com
Simple Summary Colorectal cancer with a mutation in an oncogene BRAF has paid much
attention, as it comprises a population with dismal prognosis since two decades ago. A …
attention, as it comprises a population with dismal prognosis since two decades ago. A …
[HTML][HTML] Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and others
M Bupathi, C Wu - Journal of gastrointestinal oncology, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a heterogeneous disease for which the treatment backbone has
primarily been cytotoxic chemotherapy. With better understanding of the involved molecular …
primarily been cytotoxic chemotherapy. With better understanding of the involved molecular …
Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression
IY Luk, LJ Jenkins, KL Schoffer, I Ng, JWT Tse… - Cell Death & …, 2022 - nature.com
Colorectal cancers (CRCs) often display histological features indicative of aberrant
differentiation but the molecular underpinnings of this trait and whether it directly drives …
differentiation but the molecular underpinnings of this trait and whether it directly drives …
Epidemiology and molecular-pathologic characteristics of CpG Island methylator phenotype (CIMP) in colorectal cancer
Background CpG island methylator phenotype (CIMP) forms a distinct epigenetic phenotype
in colorectal cancer (CRC). Though associated with distinct clinicopathologic characteristics …
in colorectal cancer (CRC). Though associated with distinct clinicopathologic characteristics …
Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer
J Ibrahim, K Op de Beeck, E Fransen, L Croes… - Cancer …, 2019 - Wiley Online Library
In addition to its implication in hereditary hearing loss, the Gasdermin E (GSDME) gene is
also a tumor suppressor involved in cancer progression through programmed cell death …
also a tumor suppressor involved in cancer progression through programmed cell death …
Genome-wide discovery and identification of a novel miRNA signature for recurrence prediction in stage II and III colorectal cancer
R Kandimalla, F Gao, T Matsuyama, T Ishikawa… - Clinical Cancer …, 2018 - AACR
Purpose: The current tumor–node–metastasis (TNM) staging system is inadequate at
identifying patients with high-risk colorectal cancer. Using a systematic and comprehensive …
identifying patients with high-risk colorectal cancer. Using a systematic and comprehensive …