LPA receptors: subtypes and biological actions
Lysophosphatidic acid (LPA) is a small, ubiquitous phospholipid that acts as an extracellular
signaling molecule by binding to and activating at least five known G protein–coupled …
signaling molecule by binding to and activating at least five known G protein–coupled …
[HTML][HTML] S100B's double life: intracellular regulator and extracellular signal
The Ca2+-binding protein of the EF-hand type, S100B, exerts both intracellular and
extracellular functions. Recent studies have provided more detailed information concerning …
extracellular functions. Recent studies have provided more detailed information concerning …
Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance
Lysophosphatidic acid (LPA), a water-soluble phospholipid, has gained significant attention
in recent years since the discovery that it acts as a potent signaling molecule with wide …
in recent years since the discovery that it acts as a potent signaling molecule with wide …
S100B protein in neurodegenerative disorders
Abstract “Classic” neurodegenerative disorders, such as Alzheimer's disease and
amyotrophic lateral sclerosis share common pathophysiological features and involve …
amyotrophic lateral sclerosis share common pathophysiological features and involve …
Anti-Inflammatory properties of antipsychotics via microglia modulations: are antipsychotics a 'fire extinguisher'in the brain of schizophrenia?
TA Kato, A Monji, Y Mizoguchi… - Mini reviews in …, 2011 - ingentaconnect.com
Schizophrenia is one of the most severe psychiatric diseases noted for its chronic and often
debilitating processes; affecting approximately 1% of the world's population, while its …
debilitating processes; affecting approximately 1% of the world's population, while its …
[HTML][HTML] AKAPs integrate genetic findings for autism spectrum disorders
G Poelmans, B Franke, DL Pauls, JC Glennon… - Translational …, 2013 - nature.com
Autism spectrum disorders (ASDs) are highly heritable, and six genome-wide association
studies (GWASs) of ASDs have been published to date. In this study, we have integrated the …
studies (GWASs) of ASDs have been published to date. In this study, we have integrated the …
[HTML][HTML] Interleukin-6-induced S100B secretion is inhibited by haloperidol and risperidone
Although inflammation may be a physiological defense process, imbalanced
neuroinflammation has been associated with the pathophysiology of brain disorders …
neuroinflammation has been associated with the pathophysiology of brain disorders …
[HTML][HTML] Knowledge-guided bioinformatics model for identifying autism spectrum disorder diagnostic MicroRNA biomarkers
Autism spectrum disorder (ASD) is a severe neurodevelopmental disease with a high
incidence and effective biomarkers are urgently needed for its diagnosis. A few previous …
incidence and effective biomarkers are urgently needed for its diagnosis. A few previous …
The Janus face of antipsychotics in glial cells: Focus on glioprotection
I Schmitz, A da Silva, LD Bobermin… - Experimental …, 2023 - journals.sagepub.com
Antipsychotics are commonly prescribed to treat several neuropsychiatric disorders,
including schizophrenia, mania in bipolar disorder, autism spectrum disorder, delirium, and …
including schizophrenia, mania in bipolar disorder, autism spectrum disorder, delirium, and …
[HTML][HTML] A lack of association between elevated serum levels of S100B protein and autoimmunity in autistic children
LY Al-Ayadhi, GA Mostafa - Journal of neuroinflammation, 2012 - Springer
Background S100B is a calcium-binding protein that is produced primarily by astrocytes.
Increased serum S100B protein levels reflect neurological damage. Autoimmunity may have …
Increased serum S100B protein levels reflect neurological damage. Autoimmunity may have …