Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …

Dengue is the most common arboviral disease caused by one of four distinct but closely
related dengue viruses (DENV) and places significant economic and public health burdens …

Introduction Flaviviruses are a genus of enveloped single-stranded RNA viruses that include
dengue virus (DENV), yellow fever virus, West Nile virus (WNV), Japanese encephalitis …

Background. Infection with any of the 4 related dengue virus serotypes (DENV-1–4) is
thought to result in lifelong immunity to homotypic reinfection (ie, reinfection with the same …

Dengue is the most prevalent mosquito-borne viral disease worldwide. Yet, there are no
vaccines or specific antivirals available to prevent or treat the disease. Several dengue …

We conducted an open label, dose escalation Phase 1 clinical trial of a tetravalent dengue
DNA vaccine (TVDV) formulated in Vaxfectin® to assess safety and immunogenicity. A total …

The rapid succession of the pandemic of arbovirus diseases, such as dengue, West Nile
fever, chikungunya, and Zika fever, has intensified research on these and other arbovirus …

Background Long-term homologous and temporary heterologous protection from dengue
virus (DENV) infection may be mediated by neutralizing antibodies. However, neutralizing …

Dengue virus (DENV) is a mosquito-transmitted virus that is expanding across the world.
The incidence of dengue infection, especially severe disease, has been increasing. DENV …

Dengue represents a significant and growing public health problem across the globe, with
approximately half of the world's population at risk. The increasing and expanding burden of …