Challenges and progress in nonsteroidal anti-inflammatory drugs co-crystal development

I Nugrahani, RD Parwati - Molecules, 2021 - mdpi.com
Co-crystal innovation is an opportunity in drug development for both scientists and industry.
In line with the “green pharmacy” concept for obtaining safer methods and advanced …

Combination of dissolving microneedles with nanosuspension and co-grinding for transdermal delivery of ketoprofen

D Ramadon, F Ulayya, AS Qur'ani, I Iskandarsyah… - Pharmaceuticals, 2023 - mdpi.com
Ketoprofen is an anti-inflammatory agent that may cause gastric irritation if administered
orally. Dissolving microneedles (DMN) can be a promising strategy to overcome this issue …

Pengembangan dan Validasi Metoda Disolusi Tablet Salut Enterik Ketoprofen

S Umar, H Lucida - 2022 - repository.unar.ac.id
Tablet salut enterik Ketoprofen adalah obat yang beredar luas di Indonesia. Obat ini
digunakan untuk mengatasi nyeri arthiritis tulang, rematik dan demam. Namun, sejauh ini uji …

Literature Review: Multicomponent Crystal of Active Pharmaceutical Ingredients to Improve the Solubility

ADH AH, S Umar, E Zaini - JPK: Jurnal Proteksi Kesehatan, 2023 - jurnal.pkr.ac.id
The purpose of this review was to discuss abouts active pharmaceutical ingredients (API),
formulations of drugs that are poorly soluble in water using various coformers and various …

Preparation of spray dried coamorphous solids to improve the solubility and dissolution rate of atorvastatin calcium

Y Wicaksono, VA Rosidi, SY Saragih, LS Fauziah… - Jurnal …, 2021 - journals.utm.my
Atorvastatin calcium (AC) is a statin drug used to lower cholesterol. Its crystalline form is
usually found in the market with low solubility properties. The amorphization of crystalline …

Formulation and optimization of olanzapine-carboxylic acid cocrystals orodispersible tablets: In-vitro/In-vivo study

A Elshahat, AA Hasan, HA Elghamry… - Journal of Drug Delivery …, 2024 - Elsevier
Oromucosal delivery of olanzapine (OLZ) is an optimal strategy to overcome low oral
bioavailability as well as improve medication adherence. However, its poor aqueous …

[PDF][PDF] Preparation and Solid-State Characterization of Ketoprofen-Succinic Acid-Saccharin co-Crystal with Improved Solubility

T Imanto, ER Wikantyasning, S Nurwaini… - Int J Appl …, 2024 - researchgate.net
Objective: This study aimed to improve the solubility of Ketoprofen, a non-steroidal anti-
inflammatory drug (NSAID) that belongs to the Biopharmaceutical Classification System …

Eutectic mixtures containing the active pharmaceutical ingredient ezetimibe: Phase diagrams, solid state characterization and dissolution profiles

PYG Kobata, JT Chambi, AM do Espirito Santo… - Journal of Crystal …, 2024 - Elsevier
Cardiovascular disease represents the leading cause of death worldwide, according to the
World Health Organization (WHO) report. One of the treatment strategies is the use of the …

Thermal behavior of cocrystal: A case study of ketoprofen-malonic acid and ketoprofen-nicotinamide cocrystals

Y Wicaksono, D Setyawan, AS Nugraha… - 2020 - repository.unej.ac.id
Thermal properties are essential parameters in transformations of solid state. It is useful for
estimating physicalchemical interactions that occur specifically in a multicomponent system …

[HTML][HTML] A New Multi-Component Solid of Atorvastatin Calcium with a Dipicolinic Acid Coformer for Improving the Water Solubility

Y Wicaksono, AS Nugraha, ED Irawan… - International Journal …, 2023 - ijtech.eng.ui.ac.id
A New Multi-Component Solid of Atorvastatin Calcium with a Dipicolinic Acid Coformer for
Improving the Water Solubility title Title Author Issue Keywords Current Issue : Vol 15, No 3 (2024) …