Among gynecologic malignancies, ovarian cancer is one of the most dangerous, with a high
fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …

Ovarian cancer is one of the most dangerous gynecologic malignancies showing a high
fatality rate because of late diagnosis and relapse occurrence due to chemoresistance …

There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …

Oxidative stress underlies a number of pathological conditions, including cancer,
neurodegeneration, and aging. Antioxidant-rich foods help maintain cellular redox …

Sulforaphane (SFN) extracted from broccoli sprout has previously been investigated for its
potential properties in cancers, however, the underlying mechanisms of the anticancer …

Multiple forms of regulated cell death (RCD) have been characterized, each of which
originates from the activation of a dedicated molecular machinery. RCD can occur in purely …

Background The mechanism of podocyte apoptosis is not fully understood. In addition, the
role of the inositol 1, 4, 5-triphosphate receptor (IP 3 R)/glucose-regulated protein 75 …

Mitochondria are the cytoplasmic organelles mostly known as the “electric engine” of the
cells; however, they also play pivotal roles in different biological processes, such as cell …

Prostate cancer (PCa) is the most commonly diagnosed male malignancy worldwide. Early
diagnosis and metastases detection are crucial features to diminish patient mortality. High …

Although the involvement of type 1 (IP3R1) and type 2 (IP3R2) inositol 1, 4, 5-trisphosphate
receptors in apoptosis induction has been well documented in different cancer cells and …