The immune-cell origin of hematologic malignancies provides a unique avenue for the
understanding of both the mechanisms of immune responsiveness and immune escape …

Ketone bodies are an energy substrate produced by the liver and used during states of low
carbohydrate availability, such as fasting or prolonged exercise. High ketone concentrations …

Immune-related adverse events (irAEs) associated with immune checkpoint inhibitor (ICI)
therapy may vary substantially in their clinical presentation, including natural history …

Immune checkpoint inhibitors (ICI) are cancer therapies that are approved for use in at least
19 different cancers. They function by stimulating immune cell responses against cancer …

Background Combined diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state
(HHS) secondary to immune checkpoint inhibitors (ICIs) is extremely rarely reported among …

Objective This study aimed to summarize the clinical characteristics of programmed death
receptor 1 (PD-1) inhibitor-associated type 1 diabetes so as to improve the ability of …

Background Immune checkpoint inhibitors (ICI) are promising treatment options for various
cancers. However, their use is associated with immune-related adverse events (irAEs) …

The rubric of immune-related (ir) diabetes mellitus (DM)(irDM) encompasses various
hyperglycemic disorders related to immune checkpoint inhibitors (ICPis). Beyond sharing …

Objectives. The aim of this study is to investigate in depth diabetes mellitus associated with
immune checkpoint inhibitors (DM‐ICIs) by analysing a case series. We also evaluated the …

Type 1 diabetes (T1D) is a polygenic disease and does not follow a mendelian pattern.
Inborn errors of immunity (IEIs), on the other hand, are caused by damaging germline …