As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol
and improve cardiovascular risk, but also exhibit pleiotropic effects that are independent of …

Evidence from preclinical studies suggests that the competitive HMG-CoA reductase
(HMGCR) inhibitors universally known as' statins,'in addition to being powerful drugs that …

Cancer is incurable because progressive phenotypic and genotypic changes in cancer cells
lead to resistance and recurrence. This indicates the need for the development of new drugs …

Nanotechnology has provided several advantages for the treatment of cancer. Polymeric
nanocapsules (PNCs) were proven promising in the treatment of different cancer types, such …

Statins inhibit HMG-CoA reductase by competitively inhibiting the active site of the enzyme,
thus preventing cholesterol synthesis and reducing the risk of developing cardiovascular …

Canine mammary tumours (CMTs) are the most common neoplasms in intact bitches, and
few chemotherapeutic options are available for highly invasive and metastatic tumours …

We investigated the effects of pravastatin (PRAVA) on isoprenaline (ISP) induced cardiac
fibrosis using four groups of mice: untreated control, PRAVA, ISP, ISP+ PRAVA groups. ISP …

Previous studies exploring associations between statin use and risk of multiple myeloma
(MM) showed inconsistent results. We searched for articles published in English in …

Background and aims Hyperglycemia and glucose test abnormalities are problems during
the treatment of patients with lymphoid malignancy, caused by corticosteroid therapy …

Les tumeurs mammaires canines (CMT) sont les plus fréquents néoplasmes chez les
chiennes intactes. Aucun consensus n'existe, actuellement, concernant le protocole …