Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Deciphering the genotype–phenotype map necessitates relating variation at the genetic
level to variation at the phenotypic level. This endeavour is inherently limited by the …

The genetics of phenotypic responses to changing environments remains elusive. Using
whole-genome quantitative gene expression as a model, here we study how the genetic …

Biological adaptations depend on natural selection sorting out those individuals that exhibit
characters fit to their environment. Selection, in turn, depends on the phenotypic variation …

Plasticity-led evolution is a form of evolution where a change in the environment induces
novel traits via phenotypic plasticity, after which the novel traits are genetically …

The evolution of gene expression is constrained by the topology of gene regulatory
networks, as co-expressed genes are likely to have their expressions affected together by …

The aim of this paper is two-fold. First, we propose a new computational method to
investigate the particularities of evolution. Second, we apply this method to a model of gene …

La biología evolutiva se enfoca al estudio de los patrones de variación fenotípica
heredables dentro de las poblaciones y su dinámica en tiempos transgeneracionales …

Background Research on gene duplication is abundant and comes from a wide range of
approaches, from high-throughput analyses and experimental evolution to bioinformatics …

The gene regulatory network (GRN) is essential to life, as it governs all levels of gene
products that enable cell survival and numerous cellular functions. Wagner's GRN model …