The human Y chromosome harbors genes that are responsible for testis development and
also for initiation and maintenance of spermatogenesis in adulthood. The long arm of the Y …

Azoospermia affects 1% of men, and it can be due to:(i) hypothalamic-pituitary
dysfunction,(ii) primary quantitative spermatogenic disturbances,(iii) urogenital duct …

BACKGROUND Male infertility affects> 20 million men worldwide and represents a major
health concern. Although multifactorial, male infertility has a strong genetic basis which has …

Infertility is a widespread problem and a male contribution is involved in 20–70% of affected
couples. As a man's fertility relies on the quantity and quality of his sperm, semen analysis is …

STUDY QUESTION What is the semen quality of young adult men who were conceived 18–
22 years ago by ICSI for male infertility? SUMMARY ANSWER In this cohort of 54 young …

Infertility is considered a major public health issue, and approximately 1 out of 6 people
worldwide suffer from infertility during their reproductive lifespans. Thanks to technological …

The Y chromosome harbors a number of genes essential for testis development and
function. Its highly repetitive structure predisposes this chromosome to deletion/duplication …

The clinical management of men with nonobstructive azoospermia (NOA) seeking fertility
has been a challenge for andrologists, urologists, and reproductive medicine specialists …

An accurate medical history and directed physical examination are essential in diagnosis of
male infertility. We review the hormonal assessments and specific genetic analyses that are …

The differential diagnosis between obstructive and nonobstructive azoospermia is the first
step in the clinical management of azoospermic patients with infertility. It includes a detailed …