Aging hallmarks and the role of oxidative stress
E Maldonado, S Morales-Pison, F Urbina, A Solari - Antioxidants, 2023 - mdpi.com
Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …
function of the organism and an increased risk of age-related chronic diseases such as …
Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions
KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …
head and neck, leading to complications, including mucositis, xerostomia and …
Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture
M Riegman, L Sagie, C Galed, T Levin, N Steinberg… - Nature cell …, 2020 - nature.com
Ferroptosis is a regulated form of necrotic cell death that is caused by the accumulation of
oxidized phospholipids, leading to membrane damage and cell lysis,. Although other types …
oxidized phospholipids, leading to membrane damage and cell lysis,. Although other types …
Critical phenomena in complex networks
The combination of the compactness of networks, featuring small diameters, and their
complex architectures results in a variety of critical effects dramatically different from those in …
complex architectures results in a variety of critical effects dramatically different from those in …
Radiation-induced bystander signalling in cancer therapy
KM Prise, JM O'sullivan - Nature Reviews Cancer, 2009 - nature.com
Our understanding of how radiation kills normal and tumour cells has been based on an
intimate knowledge of the direct induction of DNA damage and its cellular consequences …
intimate knowledge of the direct induction of DNA damage and its cellular consequences …
Radiation, inflammation and the immune response in cancer
Radiation is an important component of cancer treatment with more than half of all patients
receive radiotherapy during their cancer experience. While the impact of radiation on tumour …
receive radiotherapy during their cancer experience. While the impact of radiation on tumour …
Cell-cell communication in the tumor microenvironment, carcinogenesis, and anticancer treatment
BLDM Brücher, IS Jamall - Cellular Physiology and Biochemistry, 2014 - karger.com
The delineation of key molecular pathways has enhanced our knowledge of the biology of
tumor microenvironment, tumor dissemination, and carcinogenesis. The complexities of cell …
tumor microenvironment, tumor dissemination, and carcinogenesis. The complexities of cell …
Role of oxidatively induced DNA lesions in human pathogenesis
OA Sedelnikova, CE Redon, JS Dickey… - … Research/Reviews in …, 2010 - Elsevier
Genome stability is essential for maintaining cellular and organismal homeostasis, but it is
subject to many threats. One ubiquitous threat is from a class of compounds known as …
subject to many threats. One ubiquitous threat is from a class of compounds known as …
Mechanism of radiation-induced bystander effects: a unifying model
TK Hei, H Zhou, VN Ivanov, M Hong… - Journal of Pharmacy …, 2008 - academic.oup.com
The radiation-induced bystander effect represents a paradigm shift in our understanding of
the radiobiological effects of ionizing radiation, in that extranuclear and extracellular events …
the radiobiological effects of ionizing radiation, in that extranuclear and extracellular events …
Ferroptosis: Final destination for cancer?
Z Ye, W Liu, Q Zhuo, Q Hu, M Liu, Q Sun… - Cell …, 2020 - Wiley Online Library
Ferroptosis is a recently defined, non‐apoptotic, regulated cell death (RCD) process that
comprises abnormal metabolism of cellular lipid oxides catalysed by iron ions or iron …
comprises abnormal metabolism of cellular lipid oxides catalysed by iron ions or iron …