Simple Summary Cancer is a complex disease in which both cells and their environment are
altered. A tumor microenvironment contains tumor cells, normal tissue cells, blood vessels …

The extracellular matrix (ECM) is a structural framework that has many important
physiological functions which include maintaining tissue structure and integrity, serving as a …

Simple Summary Cell migration is crucial fReaor metastasis formation and a hallmark of
malignancy. The primary cause of high mortality among oncology patients is the ability of …

Carcinogenesis is a multifactorial process with the input and interactions of environmental,
genetic, and metabolic factors. During cancer development, a significant remodeling of the …

Simple Summary Cancer treatment using Salmonella is deemed a viable option since
Salmonella impedes expression of proteins relevant to tumor survival and progression. In …

Background: Lumican (LUM), a proteoglycan of the extracellular matrix, has been reported
to be involved in the regulation of immune escape processes, but the data supporting this …

The extracellular matrix (ECM) represents a complex multi-component environment that has
a decisive influence on the biomechanical properties of tissues and organs. Depending on …

Simple Summary Proteoglycans are important structural and functional components of
extracellular matrices that govern phenotype and functions of resident cells. They are often …

The processes of cell adhesion and migration fulfill crucial tasks during physiological
developmental processes, immune responses, angiogenesis, or tissue injury and …

The increase of brain neuron number in relation with brain size is currently considered to be
the major evolutionary path to high cognitive power in amniotes. However, how changes in …