[HTML][HTML] SIRT1 pathway in Parkinson's disease: a faraway snapshot but so close

GES Batiha, HM Al-Kuraishy, AI Al-Gareeb… - …, 2023 - Springer
Silent information regulator (SIRT) has distinctive enzymatic activities and physiological
functions to control cell-cycle progression, gene expression, and DNA stability by targeting …

[HTML][HTML] 'Spikeopathy': COVID-19 spike protein is pathogenic, from both virus and vaccine mRNA

PI Parry, A Lefringhausen, C Turni, CJ Neil, R Cosford… - Biomedicines, 2023 - mdpi.com
The COVID-19 pandemic caused much illness, many deaths, and profound disruption to
society. The production of 'safe and effective'vaccines was a key public health target. Sadly …

DPP-4 inhibitors and type 2 diabetes mellitus in Parkinson's disease: a mutual relationship

M Alrouji, HM Al-Kuraishy, AK Al-Buhadily… - Pharmacological …, 2023 - Springer
Parkinson's disease (PD) usually occurs due to the degeneration of dopaminergic neurons
in the substantia nigra (SN). Management of PD is restricted to symptomatic improvement …

[HTML][HTML] Cognitive impairment after long COVID-19: Current evidence and perspectives

Z Li, Z Zhang, Z Zhang, Z Wang, H Li - Frontiers in Neurology, 2023 - frontiersin.org
COVID-19, caused by the SARS-CoV-2 virus, is a respiratory infectious disease. While most
patients recover after treatment, there is growing evidence that COVID-19 may result in …

Irisin/PGC-1α/FNDC5 pathway in Parkinson's disease: truth under the throes

NH Ali, NA Alhamdan, HM Al-Kuraishy… - Naunyn-Schmiedeberg's …, 2024 - Springer
Parkinson's disease (PD) is considered one of the most common neurodegenerative brain
diseases which involves the deposition of α-synuclein. Irisin hormone, a newly discovered …

[HTML][HTML] SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway

RS Hamad, HM Al-Kuraishy, A Alexiou… - Cell Stress and …, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic caused by a novel
severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) leading to pulmonary and …

[HTML][HTML] Receptor-dependent effects of sphingosine-1-phosphate (S1P) in COVID-19: the black side of the moon

HM Al-Kuraishy, GES Batiha, AI Al-Gareeb… - Molecular and Cellular …, 2023 - Springer
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection leads to
hyper-inflammation and amplified immune response in severe cases that may progress to …

Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases: The guardian angle

HM Al-Kuraishy, MS Jabir, AK Albuhadily… - Ageing Research …, 2024 - Elsevier
The ketogenic diet (KD) is a low-carbohydrate, adequate protein and high-fat diet. KD is
primarily used to treat refractory epilepsy. KD was shown to be effective in treating different …

[HTML][HTML] Dysautonomia and small fiber neuropathy in post-COVID condition and Chronic Fatigue Syndrome

N Azcue, R Del Pino, M Acera… - Journal of Translational …, 2023 - Springer
Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and
post-COVID condition can present similarities such as fatigue, brain fog, autonomic and …

Mixed storm in SARS‐CoV‐2 infection: a narrative review and new term in the Covid‐19 era

BM Alomair, HM Al‐Kuraishy… - Immunity …, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (Covid‐19) is caused by a novel severe acute
respiratory syndrome coronavirus virus type 2 (SARS‐CoV‐2) leading to the global …