Development of Nucleic‐Acid‐Based Electrochemical Biosensors for Clinical Applications

Z Zhang, P Sen, BR Adhikari, Y Li… - Angewandte …, 2022 - Wiley Online Library
Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

Aptamer-based point-of-care diagnostic platforms

A Dhiman, P Kalra, V Bansal, JG Bruno… - Sensors and Actuators B …, 2017 - Elsevier
This review covers a broad range of well-established and novel diagnostic platforms which
are currently being considered for use in commercial point-of care (POC) diagnostics …

A graphene oxide/gold nanoparticle-based amplification method for SERS immunoassay of cardiac troponin I

X Fu, Y Wang, Y Liu, H Liu, L Fu, J Wen, J Li, P Wei… - Analyst, 2019 - pubs.rsc.org
Cardiac troponin I (cTnI) was considered as the “gold standard” for acute myocardial
infarction (AMI) diagnosis owing to its superior cardiac specificity for cardiac damage and …

Recent development of cardiac troponin I detection

X Han, S Li, Z Peng, AM Othman, R Leblanc - ACS sensors, 2016 - ACS Publications
Cardiovascular disease (CVD) has threatened human lives for decades, and a technique for
estimating and healing is still needed. There has been increasing interest in finding CVD …

Electrochemical strategies for the detection of cTnI

Z Yuan, L Wang, J Chen, W Su, A Li, G Su, P Liu… - Analyst, 2021 - pubs.rsc.org
Acute myocardial infarction (AMI) is the main cause of death from cardiovascular diseases.
Thus, early diagnosis of AMI is essential for the treatment of irreversible damage from …

Horseradish peroxidase-triggered direct in situ fluorescent immunoassay platform for sensing cardiac troponin I and SARS-CoV-2 nucleocapsid protein in serum

J Liu, G Ruan, W Ma, Y Sun, H Yu, Z Xu, C Yu… - Biosensors and …, 2022 - Elsevier
Direct in situ fluorescent enzyme-linked immunosorbent assay (ELISA) is rarely investigated
and reported. Herein, a direct in situ high-performance HRP-labeled fluorescent …

Aptamers targeting cardiac biomarkers as an analytical tool for the diagnostics of cardiovascular diseases: A review

N Komarova, O Panova, A Titov, A Kuznetsov - Biomedicines, 2022 - mdpi.com
The detection of cardiac biomarkers is used for diagnostics, prognostics, and the risk
assessment of cardiovascular diseases. The analysis of cardiac biomarkers is routinely …

Nanomaterial-based aptasensors as an efficient substitute for cardiovascular disease diagnosis: Future of smart biosensors

A Azzouz, L Hejji, C Sonne, KH Kim, V Kumar - Biosensors and …, 2021 - Elsevier
As a major cause of deaths in developed countries, cardiovascular disease (CVD) has been
a big burden for human health systems. Its early and rapid detection is crucial to efficiently …

Progress on dot-blot assay as a promising analytical tool: Detection from molecules to cells

PV Surti, MW Kim, SK Kailasa, AK Mungray… - TrAC Trends in …, 2022 - Elsevier
In recent years, dot-blot assays have received significant interest in bioanalytical sciences
and shown a significant impact on the identification of a wide variety of target analytes …

Electrochemical cardiovascular platforms: Current state of the art and beyond

S Szunerits, V Mishyn, I Grabowska… - Biosensors and …, 2019 - Elsevier
Cardiovascular diseases (CVD) remain the leading cause of death within industrialized
nations as well as an increasing cause of mortality and morbidity in many developing …