Dysfunction of mesenchymal stem cells isolated from metabolic syndrome and type 2 diabetic patients as result of oxidative stress and autophagy may limit their …

K Kornicka, J Houston, K Marycz - Stem cell reviews and reports, 2018 - Springer
Mesenchymal stem cells (MSC) have become a promising tool for therapeutic intervention.
Their unique features, including self-renewal, multipotency and immunomodulatory …

5‐Azacytydine and resveratrol reverse senescence and ageing of adipose stem cells via modulation of mitochondrial dynamics and autophagy

K Kornicka, J Szłapka‐Kosarzewska… - Journal of Cellular …, 2019 - Wiley Online Library
Obesity and endocrine disorders have become prevalent issues in the field of both human
and veterinary medicine. Equine metabolic syndrome is a complex disorder involving …

Potential of Chrysin‐loaded PCL/gelatin nanofibers for modulation of macrophage functional polarity towards anti-inflammatory/pro-regenerative phenotype

S Sadeghi-Soureh, R Jafari… - Journal of Drug Delivery …, 2020 - Elsevier
Recent reports imply that drug delivery approaches aimed to modulate the phenotypic and
functional switching of macrophages towards anti-inflammatory (M2) phenotypes have a …

Immunomodulatory properties of adipose-derived stem cells treated with 5-azacytydine and resveratrol on peripheral blood mononuclear cells and macrophages in …

K Kornicka, A Śmieszek, AS Węgrzyn… - Journal of Clinical …, 2018 - mdpi.com
Endocrine disorders, including equine metabolic syndrome (EMS), are a serious issue in
veterinary medicine and horse breeding. Furthermore, EMS was shown to affect the …

Summary on polyurethane-based drug delivery system in perspective for future implantable drug system

N Bose, K Rajappan - … Journal of Polymeric Materials and Polymeric …, 2024 - Taylor & Francis
Recent research is based on biocompatible drug delivery systems due to the need for
bioavailability, route of administration, dose dumping, and first-pass metabolism. Despite its …

Combination of resveratrol and 5‐azacytydine improves osteogenesis of metabolic syndrome mesenchymal stem cells

K Marycz, K Kornicka… - Journal of Cellular …, 2018 - Wiley Online Library
Endocrine disorders have become more and more frequently diagnosed in humans and
animals. In horses, equine metabolic syndrome (EMS) is characterized by insulin resistance …

Fabrication, characterization, and cytotoxicity of thermoplastic polyurethane/poly (lactic acid) material using human adipose derived mesenchymal stromal stem cells …

A Lis-Bartos, A Smieszek, K Frańczyk, K Marycz - Polymers, 2018 - mdpi.com
Thermoplastic polyurethane (TPU) and poly (lactic acid) are types of biocompatible and
degradable synthetic polymers required for biomedical applications. Physically blended …

Nanocrystalline hydroxyapatite loaded with resveratrol in colloidal suspension improves viability, metabolic activity and mitochondrial potential in human adipose …

K Marycz, A Smieszek, J Trynda, P Sobierajska… - Polymers, 2019 - mdpi.com
In response to the demand for new multifunctional materials characterized by high
biocompatibility, hydrogel (HG) nanocomposites as a platform for bioactive compound …

Porous 3D hydroxyapatite/polyurethane composite scaffold for bone tissue engineering and its in vitro degradation behavior

K Luo, L Wang, Y Wang, S Zhou, P Zhang, J Li - Ferroelectrics, 2020 - Taylor & Francis
In this study, a novel hydroxyapatite (HA)/polyurethane (PU) composite porous 3D scaffold
was developed by in situ polymerization. Aliphatic hexamethylene diisocyanate (HDI) as a …

Honey‐incorporated nanofibre reduces replicative senescence of umbilical cord‐derived mesenchymal stem cells

A Das, P Datta, AR Chowdhury… - IET …, 2020 - Wiley Online Library
Umbilical cord‐derived mesenchymal stem cells (UCDMSC) are attractive candidates for
cell‐based regenerative medicine. However, they are susceptible to replicative senescence …