Research progress of the effects of bisphenol analogues on the intestine and its underlying mechanisms: A review

M Zhu, R Zeng, D Wu, Y Li, T Chen, A Wang - Environmental Research, 2023 - Elsevier
Bisphenol A (BPA) and its analogues have prompted rising concerns, especially in terms of
human safety, due to its broad use and ubiquity throughout the ecosystem. Numerous …

Microbiota-directed biotherapeutics: Considerations for quality and functional assessment

EE Fekete, D Figeys, X Zhang - Gut Microbes, 2023 - Taylor & Francis
Mounting evidence points to causative or correlative roles of gut microbiome in the
development of a myriad of diseases ranging from gastrointestinal diseases, metabolic …

[HTML][HTML] MAIT cell activation is reduced by direct and microbiota-mediated exposure to bisphenols

JL Krause, B Engelmann, UN Da Rocha… - Environment …, 2022 - Elsevier
Oral uptake is the primary route of human bisphenol exposure, resulting in an exposure of
the intestinal microbiota and intestine-associated immune cells. Therefore, we compared the …

The intestinal microbiota as mediators between dietary contaminants and host health

A Cox, Z Bomstein, A Jayaraman… - … Biology and Medicine, 2023 - journals.sagepub.com
The gut microbiota sit at an important interface between the host and the environment, and
are exposed to a multitude of nutritive and non-nutritive substances. These microbiota are …

Mistle: bringing spectral library predictions to metaproteomics with an efficient search index

Y Nowatzky, P Benner, K Reinert, T Muth - Bioinformatics, 2023 - academic.oup.com
Motivation Deep learning has moved to the forefront of tandem mass spectrometry-driven
proteomics and authentic prediction for peptide fragmentation is more feasible than ever …

[HTML][HTML] Chemical mixture effects on the simplified human intestinal microbiota: Assessing xenobiotics at environmentally realistic concentrations

SB Haange, S Riesbeck, AS Aldehoff… - Journal of Hazardous …, 2024 - Elsevier
The microbial community present in our intestines is pivotal for converting indigestible
substances into vital nutrients and signaling molecules such as short-chain fatty acids …

An in vitro model system for testing chemical effects on microbiome-immune interactions – examples with BPX and PFAS mixtures

F Fischer, A Pierzchalski, S Riesbeck… - Frontiers in …, 2024 - frontiersin.org
Introduction More than 350,000 chemicals make up the chemical universe that surrounds us
every day. The impact of this vast array of compounds on our health is still poorly …

[HTML][HTML] High-throughput screening of the effects of 90 xenobiotics on the simplified human gut microbiota model (SIHUMIx): a metaproteomic and metabolomic study

V Castañeda-Monsalve, LF Fröhlich… - Frontiers in …, 2024 - frontiersin.org
The human gut microbiota is a complex microbial community with critical functions for the
host, including the transformation of various chemicals. While effects on microorganisms has …

DSS treatment does not affect murine colonic microbiota in absence of the host

JL Krause, B Engelmann, SS Schaepe… - Gut …, 2024 - Taylor & Francis
The prevalence of inflammatory bowel disease (IBD) is rising globally; however, its etiology
is still not fully understood. Patient genetics, immune system, and intestinal microbiota are …

Cytotoxic Impacts of Seven Alternative Bisphenols on Human In Vitro Cellular Models

RA Rifa, R Lavado - Chemosphere, 2024 - Elsevier
Bisphenols, common in plastics, coatings, and resins, are under scrutiny for potential
endocrine disruption. Despite banning Bisphenol A (BPA), its perceived safer alternatives …