The sine oculis (SIX) family of transcription factors are key regulators of developmental
processes during embryogenesis. Members of this family control gene expression to …

Even though the discovery of the term 'epigenetics' was in the 1940s, it has recently become
one of the most promising and expanding fields to unravel the gene expression pattern in …

Dental pulp stem cells (DPSC s) offer significant potential for use in regenerative
endodontics, and therefore, identifying cellular regulators that control stem cell fate is critical …

Introduction: Chronic kidney disease is a major health-care problem worldwide and its cost
is becoming no longer affordable. Indeed, restoring damaged renal structures or building a …

Purposes The epithelial–mesenchymal transition (EMT) plays an important role in cancer
metastasis. Previous studies have reported that valproic acid (VPA) suppresses prostate …

The generation of nephrons during development depends on differentiation via a
mesenchymal to epithelial transition (MET) of self-renewing, tissue-specific stem cells …

Upscaling of kidney epithelial cells is crucial for renal regenerative medicine. Nonetheless,
the adult kidney lacks a distinct stem cell hierarchy, limiting the ability to long-term propagate …

Results from preclinical studies are encouraging but caution is required regarding potential
human therapeutic applications because molecular, morphological and functional …

Abstracts Because of the few effective treatments for many chronic kidney diseases,
increasing consideration has been given to new regenerative therapies using stem cells …

Recent years have challenged the view that adult somatic cells reach a state of terminal
differentiation. Although the ultimate example of this, somatic cell nuclear transfer, has not …