Alzheimer's disease (AD) is prevalent throughout the world and is the leading cause of
dementia in older individuals (aged≥ 65 years). To gain a deeper understanding of the …

The cascade of amyloid formation relates to multiple complex events at the molecular level.
Previous research has established amyloid plaque deposition as the leading cause of …

Olfactory neuropathology is a cause of olfactory loss in Alzheimer's disease (AD). Olfactory
dysfunction is also associated with memory and cognitive dysfunction and is an incidental …

Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity.
Olfactory dysfunction manifests early in several neurodegenerative disorders including …

Neurodegenerative proteinopathies are characterized by formation and deposition of
misfolded, aggregated proteins in the nervous system leading to neuronal dysfunction and …

Amyloid-β peptide (Aβ) in serum is an effective biomarker for the early diagnosis of
Alzheimer's disease (AD). However, there are serious challenges to monitor subtle changes …

It is essential to identify the neuronal mechanisms of Alzheimer's Disease (AD)-associated
neuropsychiatric symptoms, eg, apathy, before improving the life quality of AD patients …

Progressive accumulation of Amyloid-β (Aβ) deposits in the brain is a characteristic
neuropathological hallmark of Alzheimer's disease (AD). During disease progression …

Alzheimer's disease (AD) is a prevalent form of dementia that affects an estimated 32 million
individuals globally. Identifying early indicators is vital for screening at-risk populations and …

Among millions of sufferers of chronic rhinosinusitis (CRS), the challenge is not only
constantly coping with CRS-related symptoms, such as congested nose, sinus pain, and …