Clinical decision support (CDS) is often cited as an essential part of pharmacogenomics
(PGx) implementations. A multitude of strategies are available; however, it is unclear which …

CADTH routinely identifies new and emerging technologies that are likely to have a
significant and meaningful impact on Canada's health care systems. Through regular …

We constructed a cost-effectiveness model to assess the clinical and economic value of a
CDS alert program that provides pharmacogenomic (PGx) testing results, compared to no …

Purpose Genomic sequencing can generate complex results, including variants of uncertain
significance (VUS). In general, VUS should not inform clinical decision-making. This study …

Primary care providers will increasingly be tasked with managing most secondary findings
from genomic sequencing, but literature exploring their capacity to manage findings beyond …

Purpose Many countries have developed clinical decision-making support tools, such as the
smart work injury management (SWIM) system in Hong Kong, to predict rehabilitation paths …

Over the last decade, utilization of clinical genetics services has grown rapidly, putting
increasing pressure on the workforce available to deliver genetic healthcare. To highlight …

PURPOSE To develop an electronic health record (EHR)–based clinical decision support
(CDS) tool to promote guideline-recommended cancer risk management among patients …

The choice of the most appropriate psychoactive medication for each of our patients is
always a challenge. We can use more than 100 psychoactive drugs in the treatment of mood …

Genetic testing can determine familial and personal risks for heritable thoracic aortic
aneurysms and dissections (TAD). The 2022 ACC/AHA guidelines for TAD recommend …