Germ cells play a unique role in gamete production, heredity and evolution. Therefore, to
understand the mechanisms that specify germ cells is a central challenge in developmental …

'The development of a multicellular organism from a single egg cell requires both the
determination of many cell types and the organization of these cells into an elaborate pattern …

Germ-line stem cells (GSCs) serve as the source for gametogenesis in diverse organisms.
We cloned and characterized the Drosophila piwi gene and showed that it is required for the …

Germline stem cells play a pivotal role in gametogenesis; yet little is known about how they
are formed, how they divide to self-renew, and how these processes are genetically …

The piwi family genes, which are defined by conserved PAZ and Piwi domains, play
important roles in stem cell self-renewal, RNA silencing, and translational regulation in …

The oskar gene directs germ plasm assembly and controls the number of germ cell
precursors formed at the posterior pole of the Drosophila embryo. Mislocalization of oskar …

Summary oskar is one of seven Drosophila maternal-effect genes that are necessary for
germline and abdomen formation. We have cloned oskar and show that oskar RNA is …

Identification and manipulation of the germ line are important to the study of model
organisms. Although zebrafish has recently emerged as a model for vertebrate …

The evolutionarily conserved Argonaute/PIWI (AGO/PIWI, also known as PAZ-PIWI domain
or PPD) family of proteins is crucial for the biogenesis and function of small noncoding RNAs …

To demonstrate the cellular and subcellular localization of mouse vasa homologue protein
during germ cell development, specific antibody was raised against the full-length MVH …