[HTML][HTML] Genome-based vaccine design: the promise for malaria and other infectious diseases

DL Doolan, SH Apte, C Proietti - International journal for parasitology, 2014 - Elsevier
Vaccines are one of the most effective interventions to improve public health, however, the
generation of highly effective vaccines for many diseases has remained difficult. Three …

[HTML][HTML] Recent findings related to immune responses against leptospirosis and novel strategies to prevent infection

F Vernel-Pauillac, C Werts - Microbes and Infection, 2018 - Elsevier
What are the new approaches and emerging ideas to prevent leptospirosis, a neglected
bacterial re-emerging zoonotic disease? How do Leptospira interrogans escape the host …

[HTML][HTML] Chemogenomics: Is a promising area for drug target and discovery

RD Amrutkar, VG Bhamare… - Journal of Modern …, 2023 - article.innovationforever.com
The latest tools of genomics and chemistry and applies them to target and drug discovery is
chemogenomoics. It is defined as the analysis of class of organic compound libraries …

[HTML][HTML] A two-component signal transduction system contributes to the virulence of Riemerella anatipestifer

Q Wang, M Chen, W Zhang - Journal of Veterinary Science, 2018 - synapse.koreamed.org
Similar to other studies of bacterial pathogens, current studies of the pathogenesis of
Riemerella anatipestifer (RA) are focused mainly on in vitro culture conditions. To elucidate …

Drug discovery: An overview

L Terfloth, S Spycher, J Gasteiger - … : Achievements and Future …, 2018 - Wiley Online Library
This chapter provides an overview on the applications of chemoinformatics in the drug
discovery process. The drug discovery process comprises the following steps: target …

Alternative biological screening methods

S Joon, RK Singla, E Tjoa, KC Parmar… - … Approaches in Drug …, 2023 - Elsevier
The emergence and re-emergence of life-threatening infectious diseases and health
ailments demand newer drug screening strategies. Novel drug discovery and screening …

Databases for Rational Design and Discovery of Multitarget Drugs

Z Wang, B Yang - Polypharmacology: Principles and Methodologies, 2022 - Springer
Rational drug design and discovery, particularly rational multitarget drug (MTD) design and
discovery, heavily relies on computational approaches exploring the Internet data resources …

A two-component signal transduction system contributes to the virulence of Riemerella anatipestifer.

WQ Wang Qing, CMM Chen MianMian, ZW Zhang Wei - 2018 - cabidigitallibrary.org
Similar to other studies of bacterial pathogens, current studies of the pathogenesis of
Riemerella anatipestifer (RA) are focused mainly on in vitro culture conditions. To elucidate …