Artificial intelligence technologies for COVID-19 de novo drug design
The recent covid crisis has provided important lessons for academia and industry regarding
digital reorganization. Among the fascinating lessons from these times is the huge potential …
digital reorganization. Among the fascinating lessons from these times is the huge potential …
Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
Computational identification of potential anti-inflammatory natural compounds targeting the p38 mitogen-activated protein kinase (MAPK): Implications for COVID-19 …
Severely ill coronavirus disease 2019 (COVID-19) patients show elevated concentrations of
pro-inflammatory cytokines, a situation commonly known as a cytokine storm. The p38 …
pro-inflammatory cytokines, a situation commonly known as a cytokine storm. The p38 …
Severe acute respiratory syndrome Coronavirus-2 GenoAnalyzer and mutagenic anomaly detector using FCMFI and NSCE
In order to deepen our understanding of the virus and help guide the creation of efficient
therapies, this study uses artificial intelligence tools to thoroughly explore the genetic …
therapies, this study uses artificial intelligence tools to thoroughly explore the genetic …
Structural interactions of phytoconstituent (s) from cinnamon, bay leaf, oregano, and parsley with SARS‐CoV‐2 nucleocapsid protein: A comparative assessment for …
I Husain, R Ahmad, S Siddiqui… - Journal of Food …, 2022 - Wiley Online Library
SARS‐CoV‐2 has been responsible for causing 6,218,308 deaths globally till date and has
garnered worldwide attention. The lack of effective preventive and therapeutic drugs against …
garnered worldwide attention. The lack of effective preventive and therapeutic drugs against …
Drug repurposing against SARS-CoV-2 using computational approaches
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
generated a critical need for treatments to reduce morbidity and mortality associated with …
generated a critical need for treatments to reduce morbidity and mortality associated with …
Molecular docking and dynamics simulation studies predict potential anti-ADAR2 inhibitors: Implications for the treatment of cancer, neurological, immunological and …
Altered RNA editing has been linked to several neurodevelopmental disorders, including
autism spectrum disorder (ASD) and intellectual disability, in addition to depression …
autism spectrum disorder (ASD) and intellectual disability, in addition to depression …
Molecular docking simulation studies identifies potential natural product derived-antiwolbachial compounds as filaricides against onchocerciasis
Onchocerciasis is the leading cause of blindness and severe skin lesions which remain a
major public health problem, especially in tropical areas. The widespread use of antibiotics …
major public health problem, especially in tropical areas. The widespread use of antibiotics …
Bioactivities and structure–activity relationships of fusidic acid derivatives: a review
J Long, W Ji, D Zhang, Y Zhu, Y Bi - Frontiers in Pharmacology, 2021 - frontiersin.org
Fusidic acid (FA) is a natural tetracyclic triterpene isolated from fungi, which is clinically used
for systemic and local staphylococcal infections, including methicillin-resistant …
for systemic and local staphylococcal infections, including methicillin-resistant …
A molecular modeling approach to identify potential antileishmanial compounds against the cell division cycle (Cdc)-2-related kinase 12 (crk12) receptor of leishmania …
The huge burden of leishmaniasis caused by the trypanosomatid protozoan parasite
Leishmania is well known. This illness was included in the list of neglected tropical diseases …
Leishmania is well known. This illness was included in the list of neglected tropical diseases …